12) Connective & Adipose Tissue Flashcards

1
Q

What is loose connective tissue?

A

Areolar tissue - tissue found in little spaces

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2
Q

What are the 2 types of dense connective tissue?

A

regular - fibres running parallel

irregular - fibres running in different directions

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3
Q

What 2 main fibres are foud in loose connective tissue?

A

collagen

elastic

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4
Q

What cell types are found in ariola connective tissue?

A

Mast cells
Adipocytes
White blood cells (Macrophages)
Fibroblasts

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5
Q

What is the function of loose connective tissue?

A

Hold the vessels in place
Stability
Permits cell migration

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6
Q

What is the function of fibroblasts?

A

Synthesise and secrete the fibres that lie in the ground substance
Form scar tissue

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7
Q

What is the function of macropahges?

A

To break down foreign organisms and cell debris

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8
Q

What is the function of mast cells?

A

Histamine - increases blood vessel wall permeability

Alergic response

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9
Q

What is the function of unilocular adipocytes?

A

Padding and shock absorber
Insulation
Energy reserve

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10
Q

What colour are unilocular adipocytes?

A

White

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11
Q

What colour are multilocular adipocytes?

A

Brown

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12
Q

What are multilocular adipocytes/brown adipose?

A

Adipocytes containing multiple lipid droplets
Cell organelles squeezed into cell centre
Increased number of mitochondria
Found in children
Oxidative phosphorylation is uncoupled to generate heat. FAST

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13
Q

What is the function of multilocular adipocytes?

A

Insulation

Energy reserves

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14
Q

What are unilocular adipocytes/white adipose tissue?

A
Contain a single lipid droplet
Normal number of mitochondria
Peripheral organelles
Found in adults
Generates heat after shivering reflex. SLOW
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15
Q

What are proteoglycans?

A

large molecules which have a GAG in the middle

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16
Q

What are GAGs?

A

long chained polysaccharides that attract water from a hydrated gel

17
Q

What are myotendinous junctions?

A

Muscle tendon junctions

18
Q

State 2 characteristics of tendons

A

Strong

Mainly made of water (68%)

19
Q

Describe the structure of irregular connective tissue

A

Contains fibroblasts

Collagen 1 fibres in all directions

20
Q

Describe the function of irregular connective tissue

A

Resists stress in all directions

21
Q

Describe the structure of regular connective tissue

A

Contains fibroblasts

Collagen 1 fibres in 1 direction

22
Q

Describe the function of regular connective tissue

A

Resists stress in 1 direction

23
Q

What are ligaments?

A

Connect bone to bone

24
Q

Describe the structure of a ligament

A

Made of parallel collagen fibres that is undulated and wrapped in loose connective tissue (fasicles)

25
Q

Describe the importance of vitamin C in collagen production

A

Vitamin C is required to make inracellular procollagen by hydroxylating proline and lysine

26
Q

What is scurvy?

A

A disease, caused by vitamin C deficiency, associated with poor wound healing and impaired bone formation

27
Q

Name 4 symptoms/signs of scurvy

A

Gum disease
bruising of skin
bleeding
poor wound healing

28
Q

What id Marfan’s Syndrome?

A

An autosomal dominant disorder where the Fibrillin 1 gene is affected, resulting in abnormal elstic tissue

29
Q

Name 3 symptoms/signs of Marfan’s Syndrome

A

Abnormally tall
extremely long and slender fingers and toes
frequent joint dislocation

30
Q

What causes the most damage to elastin?

A

UV light

Smoking

31
Q

What is osteogenesis imperfecta?

A

A disease occuring due to mutated collagen fibres that do not knit together or not enough is produced

32
Q

What are 4 symptoms/signs of osteogenesis imperfecta?

A

Short stature
Arched foot
Weakened bones
Blue schlera