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00-01-18: infectious dz > 11 - rickettsiosis, ehrlichiosis, anaplasmosis, neorickettsiosis > Flashcards

11 - rickettsiosis, ehrlichiosis, anaplasmosis, neorickettsiosis Flashcards

1
Q

(Rocky Mountain Spotted Fever)

  1. caused by what?
A
  1. Rickettsia rickettsiae
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2
Q

(Rocky Mountain Spotted Fever)

  1. most common where in USA?
A
  1. southeast, midwest
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3
Q

(Rocky Mountain Spotted Fever)

  1. transmitted by what ticks?
  2. what is the reservoir?
  3. most infections April-oct
A
  1. American Dog Tick (Dermacentor variablis)

wood tick (dermacentor andersoni)

  1. rodents
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4
Q

(Rocky Mountain Spotted Fever)

  1. bitten by tick -> organism invades what?

resulting in what?

  1. high mortality?
A
  1. vascular endothelial cells

necrotizing vascultisi, edema, dmg of organs

  1. yep
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5
Q

(Rocky Mountain Spotted Fever)

  1. common cx?
  2. thrombocytopenia is common, as is leukocytosis with a left shit, anemia, and toxic granulation of neutrophils
A
  1. fever, joint pain, ocular signs, neuro signs, petechial hemorrhages
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6
Q

(Rocky Mountain Spotted Fever)

(dx)

  1. confirmed by what?
  2. IFA is dx under what two conditions?
A
  1. serum antibody titers and PCR
  2. single high titer, or four-fold increase in paired serum samples
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7
Q

(Rocky Mountain Spotted Fever)

(tx)

  1. drug of choice?
A
  1. doxycycline (good prog if given early)
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8
Q

(canine ehrlichiosis)

  1. caused by a variety of species of Ehlichia. canis, ewingii, chaffeensis.
  2. what tick transmits E. canis? geo?
  3. E. ewingii? geo?
  4. E. chaffeensis?
A
  1. brown dog tick (Rhipecephalus sanguineous) southeast
  2. lone-star tick (amblyomma americanum) southern and central US
  3. lone-star tick; south
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9
Q

(canine ehrlichiosis)

  1. E. canis and E. chaffeensis infect what?
  2. E. ewingii?
A
  1. monocytes and phagocytes
  2. granulocytes
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10
Q

(canine ehrlichiosis)

  1. acute signs of infection occur a few weeks after tick bite and last 2 to 4 weeks - what are they?
A
  1. fever, anorexia, lethargy, oculonasal discharge, lymphadenopathy, splenomegaly, hepatomegaly, thrombocytopenia
    (e. ewingii commonly causes polyarthritis)
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11
Q

(canine ehrlichiosis)

  1. after acute phase, a long subclinical phase follows and can last form months to years.
A
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12
Q

(canine ehrlichiosis)

(dx)

  1. serology with IFA is reliable - may not see titers until 2 to 4 weeks after infection
A
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13
Q

(canine ehrlichiosis)

(dx)

  1. can see in blood luekocytes, and morulae in bone marrow cells or spirats of LN
  2. E. canis and chaffeensis are found where?

E. ewingii?

A
  1. monocytes

neutrophils

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14
Q

(canine ehrlichiosis)

  1. tx with what?
A
  1. doxycycline
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15
Q

(anaplasmosis)

  1. caused by what?
  2. transmitted by what ticks?
  3. reservoir?
  4. see where in US?
A
  1. anaplasma phagocytophilum
  2. ixodes
  3. mouse
  4. NE, upper midwest, pacific coast of california
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16
Q

(anaplasmosis)

  1. usually see cx in acutely infected animals - like what?
A
  1. fever, arthralgia, polyarthritis
17
Q

(anaplasmosis)

  1. can see moreulae where?

look identical to what?

A
  1. neutrophils

E. ewingii

18
Q

(anaplasmosis)

  1. tx of choice?
A
  1. doxycycline
19
Q

(canine cyclic thrombocytopenia)

  1. caused by what?

replicates where?

A
  1. anaplasma platys

platelets

20
Q

(canine cyclic thrombocytopenia)

  1. thought to be spread via ticks, most common in SE and gulf coast states
21
Q

(canine cyclic thrombocytopenia)

  1. see few Cx, see what in 14 day intervals?
A
  1. thrombocytopenia
22
Q

(canine cyclic thrombocytopenia)

(dx)

  1. by serology or platys
  2. can sometimes see morulae in what>
23
Q

(canine cyclic thrombocytopenia)

  1. tx of choice?
A
  1. doxycycline
24
Q

(Neorickettsiosis (Potomac Horse Fever))

  1. caused by what?
  2. can infect dogs and cats
  3. what is vector?
  4. how transmitted?
A
  1. neorickettsia risticii
  2. fluke that uses snails as an intermediate host
  3. ingestion of trematode stage in water or infected snails
25
Q

(Neorickettsiosis (Potomac Horse Fever))

  1. Cx?
26
Q

(Neorickettsiosis (Potomac Horse Fever))

  1. tx?
A
  1. doxycycline
27
Q

(salmon poisoning disease)

  1. caused by what?
  2. only occurs in dogs where?
A
  1. neorickettsia helminthoeca
  2. pacific northwest (cats don’t get)
28
Q

(salmon poisoning disease)

  1. what is vector?
A
  1. fluke (nanphyteus salmincola) infected with N. helmintoeca
29
Q

(salmon poisoning disease)

  1. how do dogs get infected?
A
  1. ingesting raw salmon containing infected fluke
30
Q

(salmon poisoning disease)

  1. Cx?
31
Q

(salmon poisoning disease)

  1. tx of choice?
  2. what elminates flukes?
A
  1. doxycycline and tetracycline
  2. praziquantel

00-01-18: infectious dz (17 decks)

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