06 - Canine Distemper

Question 1

(canine distemper)

1. caused by what virus?
2. affects a bunch of other species (not cats though)

Answer 1

1. RNA morbillivirus in the paramyxoviridae family

Question 2

(canine distemper)

(transmission)

1. main route?
2. shed how long after recovery?
3. doesn’t survive long in environment and easily killed by disinfectants

Answer 2

1. inhalation

(but virus shed in all secretions and excretions)

2. 1 to 2 weeks

Question 3

(canine distemper)

(pathogenesis)

1. infects upper resp tract -> lymphoid tissues (liver, spleen, GI tract) causing severe immunosuppression) -> viremia -> epithelial tissues and CNS
2. outcome depends on the immune response

Question 4

(canine distemper)

(immune response)

1. if immune response is rapid?

Answer 4

1. elemination with complete recovery and no clinical illness

Question 5

(canine distemper)

(immune response)

1. if partial immune response?

Answer 5

1. signs are mild and recovery occurs

may get neurologic signs from CNS localization

Question 6

(canine distemper)

(immune response)

1. if poor?

Answer 6

1. wide spread dissemitation of virus, clinical signs and high mortality rate

Question 7

(canine distemper)

(cx)

Question 8

(canine distemper)

(dx)

Question 9

(canine distemper)

(tx)

1. symptomatic and supportive
2. abx

Question 10

(canine distemper)

(prognosis)

1. high mort in young pups
2. neurologic deficits that occur are irreversible

Question 11

(canine distemper)