11/25 Flashcards
If the anticipated time from the first medical contact to PCI is >90-120 min, give __________ for STEMI if there is no contraindication
thrombolytics
Standard ACS meds
Aspirin - 162-325 mg orally
Heparin: 5,000 units (≥50 kg)
Consider
-P2Y12 inhibitor: Clopidogrel 600 mg or ticagrelor 180 mg PO
- IV nitroglycerin
- beta blockade: anterior STEM within 6 hours and will go for primary PCI (not thrombolytic therapy) and no contraindications
Consider metoprolol 5mg IV
STEMI thrombolytic contraindications
- Any prior ICH
- structural cerebral vascular lesion
- malignant intracranial neoplasm (primary or metastatic)
- Ischemic stroke within 3 mo
- aortic dissection
- Active bleeding
- Significant closed-head or facial trauma within 3 mo
- Intracranial or intraspinal surgery within 2 mo
- Severe uncontrolled hypertension dewspite therapy
For streptokinase, prior treatment within the previous 6 mo
Tenecteplase (TNK-tPA) dose
70-79 kg: 40 mg
80-89 kg: 45 mg
>90 kg: 50 mg
STEMI tPA dose
>67 kg
Alteplase (tPA): 100 mg over 1.5 h
- 15 mg IV over 1-2 min –>
- 50 mg over 30 min –>
- 35 mg over the next 60 min
If you put the patient on the monitor you must say this:
GIVE ME A RYTHEM STRIP
Do not give this cardiac med to patients receiving alteplase
nitroglycerin
increases the metabolism of alteplase and decreases the levels of alteplase and thus its efficacy
Sublingual nitroglycerin dose
0.4 mg q5min
up to 3 doses as the blood pressure allows
*If given ask for BP
Look at a v fib strip
go look
its just a bunch of pointy wide nothing
SAY this dose for defibrillation
200 J
then
300 J
then
360 J