11-22 L1 Anemia

Question 1

define anemia

Answer 1

def of RBC resulting reduced oxygen carrying capacity/reduced Red cell mass

Question 2

define Microcytic anemia

list some causes

Answer 2

• MCV<80
• Fe def, thalassemia, chronic disease, sideroblastic

Question 3

define macrocytic anemia

list some causes

Answer 3

• MCV >100
• B12/folate def, alcoholism, liver disease, reticulocytosis, hypothyroidism, myelodysplasia

Question 4

define normocytic anemia

list some causes

Answer 4

• MCV (80-100)
• chronic disease, early fe or B12/folate def

Question 5

how do you calculate MCV

Answer 5

• average volume of RBC
• MCV = (Hct(%) x 10)/RBC

Question 6

Red Blood Cell Distribution Width (RDW)

Answer 6

• Coefficient of variation of MCV

Question 7

Mean cell hemoglobin (MCH)

Answer 7

• average amt of Hgb/RBC
• MCH= Hgb/RBC

Question 8

MEan Cell Hemoglobin concentration (MCHC)

Answer 8

• average concentration of Hb in RBA
• MCHC= Hgb/Hctor MCH/MCV

Question 9

ineffective eryhtropoiesis

Answer 9

• intramedullary destrucion of hemoblogbin

destruction before it gets out

Question 10

Dyserythropoiseis

Answer 10

abnormal maturation

morphologic change

Question 11

Eryhtrokinetics

Answer 11

• plasma Fe turnover, fecal urobilinogen, Cr RBc (beta-globin)