11-18 L1 Bone Marrow

Question 1

Name the 3 granulocytes

Answer 1

• Neutrophils (50-70%)
• Eosinophils (2-4%)
• Basophils (0-1%)

Question 2

What are the 2 agranulocytes?

Answer 2

• Lymphocytes (25-28%)
• Monocytes (3-8%)

Question 3

What is the most WBC in children?

Answer 3

Remember in children lymphocytes and neutrophils are reversed.

• Lymphocytes (50-70%)
• Neutrophils (25-28%)
• Monocytes (3-8%)
• Eosinophils (2-4%)
• Basophils (0-1%)

Question 4

What site is inital hemopoiesis located in?

Answer 4

• Yolk sac
• Splanchopleura

Question 5

During the fetal months, where is the difinitive hemopoiesis produced?

Answer 5

• Liver (most)
• Spleen (second)

Question 6

Postnatally, where is definitive hemopoiesis located?

Answer 6

• Vertebra
• Sternum
• Rib
• Femur
• Tibia

Question 7

What is the life cycle for:

• RBCs
• Neurtophils
• Platelets

Answer 7

• RBCs: 120 d
• Platelets: 8-14 d
• Neutrophils: a few days

Question 8

where is the most common donor site for bone marrow extraction?

Answer 8

ilium

Question 9

What happens to granulocytes in the bone marrow pool?

Answer 9

• proliferation and maturation
• storage

Question 10

What happens to granulocytes in the peripheral blood?

Answer 10

• Marginating: 50%
• Circulating: 50%

Question 11

What happens to thrombocyte in the bone marrow pool?

Answer 11

proliferation and maturation

Question 12

What happens to the erythrocytes in teh bone marrow pool?

Answer 12

proliferation and maturation

Question 13

What happens to thrombocytes in the peripheral blood?

Answer 13

• Marginating (30%)
• Circulating (70%)

Question 14

What blood type is storage in the bone marrow?

What blood type is 100% circulating?

Answer 14

• Granulocytes
• RBCs