10a Flashcards

1
Q

Incomplete dominance

A

Mode of inheritance in which a heterozygote’s phenotype is intermediate between the phenotypes of the two homozygotes. (snapdragon color)

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2
Q

Codominance

A

Mode of inheritance in which two alleles are fully expressed in the heterozygote (blood type)

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3
Q

Mendel’s Law of segregation (2)

A

Diploid cells have pairs of genes on pairs of homologous chromosomes. The two genes are separated during meiosis and end up in different gametes.

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4
Q

Mendel’s 2nd law

A

A gene is distributed into a gamete independently of how other genes are distributed.

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5
Q

linkage group

A

Group of genes that tend to be inherited together because they are on the same chromosome

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6
Q

Linked genes

A

genes on the same chromosome

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7
Q

linkage map

A

diagram of gene order and spacing on a chromosome, based on crossover frequencies

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8
Q

Product rule

A

States that the chance that two independent events will occur equals the product of the individual chances that each event will occur.

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9
Q

True breeding

A

Always producing offspring identical to the parent for one or more traits (homozygous)

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10
Q

Locus

A

The physical locatioin of a gene on a chromosome

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11
Q

Allele

A

One of the alternative forms of a specific gene

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12
Q

Hybrid

A

Producing a mix of offspring for one or more traits (heterozygous)

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13
Q

Mutant

A

A phenotype, genotype or allele resulting from a mutation in a gene

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14
Q

Dominant allele

A

An allele that exerts its effects whenever it is present

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15
Q

Recessive Allele

A

An allele whose effect is masked if a dominant allele is also present

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16
Q

Test cross

A

A mating between and individual of unknown genotype and a homozygous recessive individual. The genotype of the unknown parent can be deduced from the phenotype ratio of the offspring.

17
Q

Polygenic

A

Phenotype reflects the activity of more than one gene. (i.e. eye color)

18
Q

Homozygous

A

Possessing two identical alleles for a gene

19
Q

Heterozygous

A

Possessing two different alleles for a gene

20
Q

Autosomnal Dominant

A

Inheritance pattern of a dominant allele on a chromosome. Expressed in heterzygotes, One or both parents must also have the disorder. (Huntington’s)

21
Q

Autosomnal Recessive

A

Inheritance pattern of a recessive allele on a chromosome - requires that a recessive allele by passed down by both parents. (albinism)

22
Q

X-inactivation

A

Turning off all but one X chromosome in each cell of a mammal (usually female) in early development.

23
Q

X-linked

A

Describes traits controlled by genes of the X chromosome

24
Q

Pleiotropy

A

One gene has multiple effects on the phenotype. (i.e. one protein is used or affects
many parts of the body. (Marfan/connective tissue)

25
Q

Epistasis

A

One gene masks another gene’s expression (i.e. baldness hides the effects of a widow’s peak)

26
Q

Phenotype

A

Observable characteristic of an organism

27
Q

Genotype

A

An individual’s combination of alleles for a particular gene

28
Q

What is P, F1, F2

A

The P generation is the parental or starting generation. F1 and F2 (filial) refer to the first and second generations, respectively.

29
Q

What is a monohybrid cross, and what are the genotypic and phenotypic ratios expected in the offspring of the cross?

A

A monohybrid cross is a mating between two individuals that are each heterozygous for one gene. The genotypic ratio expected in a monohybrid cross is 1:2:1 (homozygous dominant : heterozygous : homozygous recessive); the phenotypic ratio is 3:1 (dominant:recessive).

30
Q

What is a dihybrid cross, and what is the phenotypic ratio expected in the offspring of the cross?

A

In a dihybrid cross, two individuals that are each heterozygous for two genes are mated. The phenotypic ratio that is expected is 9:3:3:1 (dominant for both genes: dominant for one gene and recessive for the other: recessive for one gene and dominant for the other: recessive for both genes).

31
Q

Punnett square use?

A

Punnett squares show the genotypes of each parent as well as the genotypes of potential offspring. Phenotypic and genotypic ratios of offspring can be predicted from the data in Punnett squares.

32
Q

X-linked dominant disorders

A

hairy, rickets, retinis pigmentosa

33
Q

X-linked recessive disorders

A

RG colorblindness, hemophilia, Duchenne

34
Q

Centromeres divide in?

A

Mitosis/anaphase and Meiosis 2/Anaphase 2

35
Q

Describe and differentiate between Diploid vs. Haploid

A

A diploid cell (2n) has two full sets of chromosomes, with one set coming from each parent. A haploid cell (n) has only one set of chromosomes.

36
Q

Non-mendelian inheritance

A

Codominance, incomplete dominance, pleiotropy, epistasis