1: Microbial World and You Flashcards
What does the term “microorganisms” include?
bacteria, fungi, protozoans, microscopic algae, and viruses
How do the majority of microbes affect mankind?
they are of extreme benefit, only a few are pathogenic
How are microbes beneficial?
part of the food chain; Break down wastes and recycle important elements in the soil and water; photosynthesis; synthesize vitamins in our gut; commercial industry
Which vitamins do microbes synthesize in our gut?
some B vitamins and vitamin K
Essential in order for the liver to produce several important blood clotting factors
Vitamin K
How are microbes used in commercial industry?
Industrial chemicals; alcoholic beverages; antibiotics; food processing; enzymes; insulin production
allows the survival of bacteria with antibiotic-resistant genes, such as MRSA
misuse of antibiotics
MRSA
methicillin-resistant staphylococus aureus. Multiple-resistance, not just methicillin!
Caused by prolonged antibiotic use, causes spontaneous hemorrhage
Vitamin K Deficiency
first name of a microorganisms that is typically a large group
genus
second name of a microorganism that is a more exact designation of specific members
species
a bacterium commonly found on human skin
staphylococcus aureus
staphylo=?, coccus=?, aureus=?
staphylo=cluster; coccus=round; aureus=golden
genomics
study of all of an organism’s genes
relatively new field or study and has led to reclassification of many microorganisms that were previously named solely on their observed behavior
genomics
do NOT have a true membrane bound nucleus
Prokaryotes
Bacteria and Archaea
Prokaryotes
prokaryotes that do not cause human disease but are typically found in extreme environments
archaea
DO have a true membrane-bound nucleus
Eukaryotes
Fungi, Protozoans, Algae, and Multicellular animal parasites
Eukaryotes
yeasts, molds, fleshy fungi
Fungi, eukaryotes
composed of hyphae that branch and intertwine
molds
long filaments
hyphae
amoebas, flagellates
protozoans, eukaryotes
some of which are parasites
protozoans
organisms that derive nutrients from living hosts
parasites
photosynthetic eukaryotes with a wide variety of shapes
algae
helminths
worms, multicellular animal parasites
very different form prokaryotes and eukaryotes and are very small
viruses
Types of Microorganisms
Prokaryotes, Eukaryotes, and Viruses
acellular and structurally very simple
viruses
only considered to be living when they are multiplying in a host cell, and are inert when outside a host cell
viruses
scientific term for viruses that only demonstrate life when inside a host cell
Obligate Intracellular Parasites
Developed crude multiple-lens microscope and examined cork. This led to the “cell theory”
Robert Hooke
The idea that all living things are composed of cells.
The Cell Theory
Used a simple single lens microscope to examine actual microbes
Anton van Leeuwenhoek
life arising from non-living matter
Spontaneous Generation
had jars of decaying meat, disproving Spontaneous Generation
Francesco Redi
very primative microorganisms found in Yellowstone
archaea
living cells only arise from pre-existing living cells
biogenesis
his experiments formed the basis of aseptic techniques
Louis Pasteur
disproved the theory of spontaneous generation through his invention of the “swan-necked” flasks
Louis Pasteur
period of 60 years from 1857-1914 where many discoveries in microbiology were made
Golden Age of Microbiology
belief that life is everywhere
panspermia
process by which yeasts can produce alcohol in the absence of air
fermentation
In the presence of air, bacteria change the alcohol in a beverage into what?
vinegar (acetic acid)
process by which mild heating after the alcohol is produced kills most of the spoilage bacteria. used to treat alcoholic drinks and milk
pasteurization
one cause of silkworm disease
protozoan
Joseph Lister used this during and after surgery to kill bacteria harmful to patients
phenol (carbolic acid)
a set of rules to prove a particular microbe causes a particular disease
Koch’s postulates
cowpox virus
vaccinia, provides protective cross-reactive immunity to smallpox virus
smallpox virus
variola
Edward Jenner
discovered variola vaccination (1st)
What is chicken cholera caused by?
a bacterium
discovered a method to produce other vaccines
Louis Pasteur
What was Edward Jenner’s gift of character that enabled him to make his important discovery?
listened to people and willing to experiment
term for ‘disease-causing’
virulent
pathogenic microbes can lose their ability to cause disease
become attenuated (weakened) and avirulent. can be used in vaccines (lose pathogenicity, but retain immunogenicity)
the treatment of ANY disease by chemical substances
chemotherapy
two general types of chemotherapeutic agents
Synthetic drugs and antibiotics
synthetic drugs
made from chemicals in the laboratory
antibiotics
made by microbes naturally
The first synthetic drugs
Salvarsan, Quinine, and sulfa drugs
what does Salvarsan treat?
syphilis. (salvation from syphilis and contains arsenic) discovered by Paul Ehrlich
where does Quinine come from?
tree bark
study of bacteria
bacteriology
study of fungi
mycology
study of protozoa and parasitic worms
parasitology
the study of all of an organism’s genes. advances have allowed scientists to classify according to genetic relationships with other bacteria, fungi, and protozoa
genomics
study of viruses, which are typically very small and are a different form of “life”
virology
study of the immune response to foreign substances
immunology
AIDS
acquired immunodeficiency syndrome
method by which genetic material from different organisms can be recombined
Recombinant DNA technology
bacteria modified to produce human proteins, such as insulin
example of Recombinant DNA technology