1. Kidney embryology Flashcards
intermediate mesoderm gives rise to
urogenital ridge
Urogenital ridge gives rise to … (and then )
nephrogenic ridge –> develops into 3 steps of nephric structure —> a. pronephros b . mesonephros c. metanephros
sets of nephric structure ( and area)
- pronephros ( upper - cranial most)
- mesoneprhros ( middle)
- metanephros ( lower -caudal most)
pronephros - time
apperas at week 4 and then degenerates
pronephros - function
not functional in humans 5
pronephros develops by
the differentiation of mesoderm within the nephrogenic cord to form pronephric tubules and the pronephric duct
mesonephros develops by
the differentiation of mesoderm within the nephrogenic cord to form mesonephric tubules and the mesonephric duct (wolffian duct)
mesonephric duct is AKA
Wolffian duct
mesonephros function
- interim kidney for 1st trimester
2. later contributes to male genital center ( mesonephric duct)
mesonephros - regression
most of mesonephric tubules regress, but the mesonephric duct ( Wolffian duct ) persists to open into urogenital sinus
Metanephros time
1st appears in5th week of gestation –> nephrogenesis continuous through 32-36 weeks of gestation
metanephros is functional in fetus in (time)
week ten
metanephros is consist by
- ureteric bud
2. metanephric parenchyma ( metanephric blastema)
metanephros is consist by … ( developed by)
- ureteric bud –> derived from caudal end of mesonephric duct
- metanephric parenchyma ( metanephric blastema)–. condensation of mesoderm within nephrogenic cord
metanephros is consist by (gives rises generally )
- ureteric bud –. collecting system
2. metanephric parenchyma ( metanephric blastema)—> nephron