Y2 ARC- Antenatal results and choices

Question 1

How many women access ARC support every year?

Answer 1

6500 women

Question 2

What does ARC involve?

Answer 2

NIPT
Screening results
Diagnosis
ToPFA

Question 3

What is the most import ant part of effective care?

Answer 3

Communication

Question 4

What additional tests are done in pregnancy?

Answer 4

1st trim- CUBS (combined ultrasound and biomedical screening)
2nd trim- AFP/hCH/UE3?InhA screening
NIPT as second line screening
Routine anomaly scan at 20w.

Question 5

It is super important to let everyone know that all of these screening tests are completely volontary.

Answer 5

TRUE

Question 6

NIPT

Answer 6

Non-Invasive prenatal testing, checks babys blood cells in maternal bloodstream and is 99 % accurate.

Question 7

What is the risk in % for CVS and Amniocentesis?

Answer 7

0.5%

Question 8

Pregnancy screening

Answer 8

1st trim: Family origin questionnaire and haemoglobinopathy screen < 12 weeks.
11+2-14+1 Common trisomy’s
2nd trim: 14+2- 20+0 (Downs syndrome)
Fetal anomaly scan 18-20 weeks.

Question 9

How common are T13, T18 and T21

Answer 9

Down syndrome (trisomy 21)
1 in 1000 live births

Edwards syndrome (trisomy 18)1 in 3000 live births

Patau syndrome (trisomy 13)
1 in 5,000 live births

Question 10

Are these Sporadic/inherited

Answer 10

Most cases are sporadic
Some are due to unbalanced translocation
-Whole chromosome trisomy (Robertsonian translocation)
-Partial chromosome trisomy (reciprocal translocation)
A few due to mosaicism

Question 11

Prenatal invasive tests

Answer 11

Chorionic Villus Sample/Amniocentesis
QF-PCR
Microarray
Targeted test for known genetic conditions