Wounds & Fractures Flashcards
T/F: epithelialization can be seen histologically within the first days of injury, however it appears grossly around day 7 during the proliferation phase.
true
how long do the following phases approximately last?
A. Inflammation
B. Proliferation
C. Maturation/Remodeling
A. Inflammation = day 0-7
B. Proliferation = day 4-14
C. Maturation/Remodeling = day 14+
What 3 events occur in the VASCULAR portion of the inflammation phase of wound healing? These things occur within the first 15 minutes of the wound occurring.
List them in the correct order of events.
- vasoconstriction (platelets aggregate to stop bleeding)
- vasodilation (with fibrocellular clot)
- polymorphonuclear leukocytes (phagocytize bacteria and release proteases)
What occurs in the debridement phase of wound healing?
First, neutrophils come in and destruct.
Then, macrophages phagocytize necrotic tissue and release proteases and kill bacteria.
T/F: debridement phase of wound healing is influenced by the presence of necrotic tissue and debris.
true
what is the major cell and cell purpose within the proliferation phase of wound healing?
fibroblasts to synthesize extracellular matrix and collagen;
Granulation tissue is formed
what is granulation tissue composed of?
Capillaries and fibroblasts
NO nerve tissue.
In what large animal species does granulation tissue get out of control in? Why is it important?
horses – this is called proud flesh.
Proud flesh inhibits epithelialization
A _____ has decreased strength, vascularity, and cellularity.
scar
What type of wound is a right flank pyloro-ometopexy of abomasum?
clean wound (surgical wound that we create)
what type of wound is a c-section?
clean-contaminated (surgical wound in which a luminal organ was entered, but no spillage)
what type of wound are the following procedures: barnes dehorning, castration, rumen cannulation, mammary vein laceration repair?
contaminated wounds
What type of wound are the following: wire injuries, puncture wounds, equipment wounds, calving injuries, and “found her this way”
dirty
what should you clean a wound with after you have clipped the fur?
mild neutral soap (ivory) and water to remove gross debris on actual wound
and can use surgical scrub for intact skin around wound (esp if suturing).
You should never enter joints for wound repair unless…
you have sterile instruments and practice asepetic technique.
what is the perfect lavage fluid to use for wounds?
isotonic, warm LRS or 0.9% saline onto wound at 8 psi
In the last liter, add 25 mL of chlorhexidine for residual effect.
T/F: scraping/rubbing the wound is the best way to perform debridement
false – this is not recommended; the best way is to perform sharp excision of the entire surface of the wound with copious lavage.
what suture should you use when performing a primary closure of a wound?
remember there are 2 layers
muscle & fascia: absorbable (chromic gut)
skin: non-absorbable monofilament (polyamid or braunamid)
why do we use tension relieving sutures such as vertical mattress and near-far-far-near?
excessive tension can cause pressure necrosis, suture failure, interrupt circulation, and inhibit wound healing
why vertical mattress over horizontal?
vertical mattress sutures do not constrict as many peripheral healing capillaries.
Dead space is the space left in a wound following a surgical procedure that can fill with blood or serum and increase risk of infection, prevent tissue apposition, and prevent healing.
How is dead space managed in large animals?
suture ALL tissue planes – tack upper plane to lower plane of external fascia.
Can also use drains or pressure dressings but these are less common in large animals.