wound healing and reconstruction Flashcards
what is an abrasion
- loss of epidermis and maybe some dermis
- not full tickness
- due to blunt trauma/shearing
what is an avulsion
- tearing of tissues from attachments but usually left as flap
- on limbs: degloving
what is an incision
- Created by a sharp object
- minimal trauma
- all surgical wounds
what is a laceration
- similar to incision but not controlled
- tearing of wound creating irregular defect
what is a puncture
- penetrating wound
- superficial damage may be minimal
- deep damage may be substantial (organs etc.)
what type of wound is this
abrasion
what type of wound is this
avulsion/laceration
what type of wounds are these
incisions
what type of wound is this
puncture
discuss vascular supply of the skin
- 3 layers of supply to all 3 layers of skin (deep, middle and superficial
- subdermal plexus is major netwrok supplying blood from direct cutaneous artery
- direct cutaneous artery branches off to supply skin
- if cut, patch of skin it was feeding will die
what are the 3 phases of wound healing
- inflammation/hemostasis
- fibroplasia
- maturation
what occurs during the inflammatory phase of wound healing and how can you tell you are looking at a wound in this phase
- transient vasoconstriction (prevet bleeding out) then vasodilation (to get as many clotting factors and inflam cells as possible to site)
- increased capillary permeability
- activation of intrinsic and extrinsic clotting cascade
- chemotaxis of inflammatory cells
- neutrophils called to site followed by macrophages (macros send signals for more cells to accumulate)
can tell: fresh blood, fresh edges, no granulation tissue
what occurs during the repair phase and how can you identify that you are looking at a wound in this stage
- fibroplasia
- cessation of inflammatory phase
- fibroblast migration (contact inhibition = cells meet eachother and signal to stop spreading and production of proteoglycans, collagen and elastin)
- wound contractions
- epithelialisation
Can tell: granulation tissue and pink epithelisation around edges
what occurs in the maturation/remodelling phase and how can you tell you are looking at a wound in this phase
- matrix synthesis and matrix degradation
- cross linking of collagen type 1 and 3
- inrease in tensile strength
- scar formation
- takes weeks to months
can tell: dry scab, no visible granulation tissue (or very little), scar
what species has slower wound healing
cats: granulation tissue forms slower and wound strength therefore less at same healing timeperiods
list systemic factors that negatively impact wound healing
- old age
- medications (steroids)
- radiation
- co-morbidities (cushings and diabetes)
- nutrition
list local factors that negatively affect wound healing
- seroma
- neoplasia
- foreign material
- self trauma
- necrostic tissue
- contamination infection
you are presented with a patient with a wound. what will you do first
assess the patient for other injuries
- always stabilise patient first, dont miss something more traumatic inside that can kill the patient by being distracted by the wound!!!
- TPR, imaging, bloodwork, history,
what things will you look for when assessing a wound
- level of contamination (soil/organic material within?)
- type of tissue affected (just skin? muscle? bone? tendon?)
- vascular compromise (are the tissues viable)
- foreign material (hair and sutures)
most animal wounds are contaminated. how do you distinguish contaminationf from infection
for a wound to be infected, the bacterial must be present in large amounts for period of time. contamination is considered as bacteria where it doesnt belong. it takes 6-12 hours for bacteria to divide and more than 12 hours for bacteria to invade the tissue
what factors influence bacterial contamination of a wound
- vascular supply (reduced ability to fight infection)
- devitalised tissue (increased bacteria growth)
- foreign body (reduced ability to fight infection)
- type of contamination (bite vs cut from glass?)
- type of bacteria
what are the goals of wound management
- promote healing
- convert contaminated into “clean”
- control infection
what are the principles of wound management
- clip hair to protect wound
- debride wound
- antimicrobial therapy
- open vs closed healing
discuss wound levage
- purpose to dilute bacteria and flush out FB
- encourages healing
- isotonic solutions are best (can use water but could kill good cells)
- always culture AFTER levage