Wound Healing Flashcards
1
Q
Enzyme necessary for replacement of type III collagen with type I collagen in scar formation
+ cofactor
A
collagenase
zinc is cofactor
2
Q
Granulation tissue is made up of
A
type III collagen
capillaries
myofibroblasts
3
Q
Healing by
primary intention
secondary intention
A
1˚ intention: approximate edges
2˚ intention: granulation tissue fills in gap, no approximation of edges
4
Q
Complication of healing by 2˚ intention
A
myofibroblasts may contract scar
5
Q
TGF-β function
A
inhibits inflammation
6
Q
Fibroblast growth factor also important in
A
angiogenesis
7
Q
Dehiscence is
A
rupture of wound
8
Q
Hypertrophic scar
A
excess production of scar tissue
localized
9
Q
Keloid scar
A
excess production of scar tissue out of proportion for wound
