Autoimmune Disorders Flashcards
1
Q
Anti-centromere Ab
A
limited scleroderma (CREST)
2
Q
ANA
A
in many diseases, sensitive but not specific
SLE (screening), Sjögren
3
Q
Anti-histone Ab
A
drug-induced SLE
4
Q
Anti-phospholipid Ab
A
falsely prolonged PTT (often in SLE)
actually hypercoag state
5
Q
Anti-dsDNA Ab
A
specific test for SLE
6
Q
Anti-ribonucleoprotein Ab
A
Sjögren
anti-SSA and anti-SSB
Sjögren Syndrome Antigen
7
Q
Anti-SSA/B Ab
A
in Sjögren and SLE commonly
crosses placenta –> neonatal SLE
congenital heart block
8
Q
Anti-DNA topo I Ab
A
diffuse scleroderma
