wound healing Flashcards
what are the four phases of wound healing
-hemostasis
-inflammatory
-proliferative
-maturation
describe hemostasis
-first phase (occurs within 48 hours after wound)
-vasoconstriction
-exudate producation
-platelet activation -> clot formation
desrcibe the inflammatory phase
-vasodilation (increases drainage)
-phagocytosis (wound is flooded with WBCs)
-localized inflammatory response (looks like infection with redness, warmth, swelling, and tenderness)
-lasts 4-6 days
describe proliferative phase
-rebuilding, new tissue fills wound space
-lasts 3-24 days
-fibroblasts ad growth factor create collagen and blood vessels
-granulation tissue formation (not always visible, thin layer, super vascular)
describe maturation phase
-can take up to two years
-collagen matures
-scar tissue is created (less elastic and string than surrounding tissue, avascular with no hair or sweat)
in which phase of the wound healing process is new tissue built to fill the wound space, primarily through the action of fibroblasts?
proliferation phase
name some different types of wound healing
-primary intention (primary union)
-secondary intention (contraction and epithelialization)
-tertiary intention (delayed closure)
describe primary intention (primary union)
-clean incision
-minimal tissue loss
-early suture
-“hairline” or minimal scarring
describe secondary intention (contraction and epithelialization)
-gaping irregular wound
-heals from the bottom up
-epithelium grows over scar
-scarring and infection are more prevalent
-examples may include pressure injuries, deep lacerations, or burns
describe tertiary intention (delayed closure)
-wound is intentially left open for a period of time
-may be unable to close or need to monitor for bleeding
name some systemic factors that affect wound healing
-age (old ppl take long to heal)
-nutrition (protein, vitamins A & C, zinc)
-circulation and oxygenation
-health status (diabetes, shock, immunosupression, obesity, chemotherapy, steroids, antibiotics)
name some local factors that affect wound healing
-moisture (desiccation or maceration)
-trauma **
-edema** (interferes with blood flow)
-infection (increased stress to the body and demand of resources)
-bleeding (clots may need to be evacuated)
-necrosis (no healing with dead tissue)
-biofilm (thick collection of bacteria, can make wound difficult to treat)
what is desiccation
drying, dehydrated, crust
what is maceration
excessive moisture
name some complications of wound healing
-hemorrhage or hematoma
-dehiscence or evisceration
-infection
-fistula