Women's health Flashcards
s/s of ectopic pregnancy
low back or abd pain/cramping
risk factors for ectopic pregnancy
hx of PID, hx of tubal ligation, previous ectopic pregnancy, IUD
hCG levels in ectopic pregnancy
rise at the same rate as normal pregnancy but plateau in 4-6 weeks
s/s of breast cancer
painless, firm, fixed mass; dimpling of skin (peau d’orange), nipple retraction, clear nipple discharge
risk factors for breast cancer
age greater than 50, first degree family hx, early menarche, late menopause, nulliparity, obesity, Jewish
s/s of Paget’s disease (ductal carcinoma)
scaly, red rash on the nipple that doesn’t heal; itchy
s/s of inflammatory breast cancer
acute onset of red, swollen, warm area in breast of young woman
risk factors for ovarian cancer
age greater than 60, hx of breast cancer, family hx
s/s of ovarian cancer
bloating, dyspepsia, abdominal pressure/pain, urinary frequency, constipation
Has been shown to decrease risk of ovarian cancer
OCP, multiparity, breastfeeding
women with hx of breast cancer have a high risk of
ovarian cancer
where the majority of breast cancer is located
tail of spence
bright red tissue with an irregular surface on top of the os; common in adolescents
cervical ectropion
s/s of uterine fibroids
heaving menstrual bleeding, pelvic pain/cramping, spotting
follicular phase (days 1-14)
FSH stimulates estrogen production that stimulates the growth of endometrial lining
Ovulatory phase (day 14)
LH is secreted
Luteal phase (days 14-18)
Progesterone is the predominant hormone that stabilizes the endometrial lining
Menstruation phase
If not pregnant, both estrogen and progesterone fall, causing menses
fertile time in a women is
5 days before and 1-2 days after ovulation (near day 14)
Menstrual cycle phases
follicular phase, ovulatory phase, luteal phase, menstruation
ASCUS result on pap
If woman less than 24, repeat pap in 1 year. If woman greater than 24, then order HPV reflex, if positive then colposcopy
monophasic pills (Loestrin 1/20)
21 consecutive days of same dose of estrogen and progesterone
Triphasic pills (Ortho Tri-cyclen)
21 days of active pills with hormones that vary every week
pills that can be adjunctively used for acne
triphasic (Ortho Tri-cyclen)
extended cycle pill (Seasonale)
contains 3 months of estrogen/progesterone with 7 day pill-free interval
Uses drospirenone (a spironolactone analog) instead of progestin. Used for women with acne, PCOS, hirsutism, or PMDD
Yaz or Yasmin
Yaz/Yasmin have ___ active pills and ___ placebo pills
24; 4
Yaz/Yasmin have a high risk of
hyperkalemia, DVT
OCP safe for breastfeeding women
progestin-only pill (minipill)
absolute contraindications of oral contraceptive pills mneumonic
My CUPLETS My: migraines with focal neurologic aura C: CAD or CVA U: undiagnosed genital bleeding P: pregnant L: high LFTs E: Estrogen-dependent tumor T: thrombus or emboli S: smoker age 35 or older
advantage of OCP is a lower risk of
endometrial and ovarian cancer
Instructions on starting OCP
- Take first pill on first Sun of menstrual period
- Take the pill on the first day of period
- Use back up method for the first 2 weeks of first pack
s/s of endometriosis
severe cramping and heavy periods in young women
Education if pissed 2 consecutive days of OCP
take 2 today, then 2 tomorrow; use condoms for the rest of the cycle
these drugs can decrease efficacy of OCP
anticonvulsants, antifungals, ampicillin, tetracycline, St. john’s wort
administration of morning after pill
Effective up to 72 hours after unprotected sex, but most effective if taken within first 24 hours
danger signs of OCP
ACHES: Abdominal pain; Chest pain; Headaches; Eye problems, change in vision; Severe leg pain
administration of copper containing IUD
Paraguard; effective for up to 10 years; may cause increased bleeding/spotting
administration of hormone-containing IUD
effective for up to 5 years
____, a hormone-containing IUD contains _____
Mirena; levonorgestrel
contraindications of IUD
hx of PID, hx of ectopic pregnancy
Education about IUD
check for string after each menstrual period
Administration of Depo Provera
injection every 3 months, start on first 5 days of cycle
Education about Depo Provera
can cause amenorrhea d/t lack of estrogen; can cause osteoporosis
Women should not use Depo Provera if
they plan on getting pregnant in the next year as it causes delayed return of fertility
black box warning with Depo Provera
should not be used for more than 2 years d/t increased risk of osteoporosis
contraindication of Depo Provera use
anorexia
administration of diaphragm
Must be used with spermicidal gel; leave in for 6-8 hours after intercourse (can remain for up to 24 hours)
Nuvaring contains
both estrogen and progesterone
Administration of Nuvaring
left for 3 weeks, then removed for 1 week.
Ortho Evra patch contains
both estrogen and progesterone
administration of Ortho Evra patch
applied once a week for 3 weeks
risks with Ortho Evra patch
higher risk of VTE d/t high levels of estrogen
s/s of too much estrogen
nausea, bloating, breast tenderness
s/s of too much progestin
increased appetite, weight gain, fatigue
woman with asymptomatic gonorrhea or chlamydia with a IUD
can be treated with IUD in place
Implanon/Nexplannon contains
progestin
Implanon/Nexplannon administration
changed every 3 years
Education about Implanon/Nexplannon
Quick return of fertility after removal.
s/s of fibrocystic breasts
breast tenderness and lumps that begin up to 2 weeks before period, then goes away once period begins; lumps are symmetrical, tender, mobile, and rubbery.
trx for fibrocystic breasts
wear bra daily, decrease sodium and caffeine before periods
s/s of PCOS
hirsutism, irregular periods, acne
diagnostics for PCOS
LH/FSH greater than 2.5:1; increase in testosterone, prolactin, high fasting glucose; transvaginal US
trx for PCOS
low dose OCP, spironolactone, Metformin
pathophysiology of PCOS
high insulin and obesity cause an increase in androgen production and decrease SHBG (bind to and excrete testosterone).
risk factors of candida vaginitis
diabetics, HIV, steroids, amoxicillin, pregnancy
s/s of candida vaginitis
white cheese-like discharge, itching and redness
diagnostic for candida vaginitis
KOH prep, vaginal pH less than 4.5
treatment for candida vaginitis
diflucan x1, terconazole vaginal cream
If patient gets candida from this atbx: ____, recommend to _____
amoxicilin; daily yogurt and lactobacillus pill
replacement of normal, hydrogen-peroxide Lactobacillus with anaerobic bacteria
BV
These are NOT considered STDs
BV, candida vaginitis
s/s of BV
fishy vaginal odor after intercourse; milk-coated vaginal walls
diagnostics with BV
vaginal pH greater than 4.5;
“clue cells” (squamous epithelial cells) on wet mount;
positive “whiff test”
trx for BV
metronidazole 500 mg bid x 7 days; avoid with alcohol
clindamycin cream x 7 days
recurrence of BV
common; perform test of cure 2-3 weeks after therapy
s/s of trichomoniasis
pruritic, red vulvovaginal area; gray/green frothy discharge; strawberry cervix
diagnostic for trichomoniasis
vaginal pH greater than 4.5; motile, flagellated trichomonads on saline wet mount
trx for trichomoniasis
metronidazole 2 g PO x 1, treat sexual partners
s/s of atrophic vaginitis
vaginal dryness, itching, pain with intercourse
atrophic vaginitis may cause this to be abnormal
pap smear (atrophic changes)
trx for atrophic vaginitis
estrogen cream; need progesterone supplementation if intact uterus
risk of osteopororis
postmenopausal women, chronic steroids, autoimmune disorders, low testosterone, hyperthyroidism, alcoholics, smokers
perform DEXA scan every
every 1-2 years with those on trx; otherwise every 2-5 years
trx for osteoporosis
weight bearing exercise (walking, jogging, biking, aerobics); calcium with vit D (1200 mg/day) and vitamin D3 (800-1000 IU daily)
side effects of biphosphonates
PUD, esophagitis
biphosphonates
Fosamax (alendronate), Actonel (risedronate)
administration of biphosphonates
take right upon awakening with full glass of water;
wait 30 min before lying down;
do not crush/split tablets;
never take with other meds
Evista (raloxifene)
SERM for osteoporosis
approved for use only after menopause; NOT used to trx menopausal symptoms
SERM
Hormone replacement therapy increases risk of
DVT, heart disease, endometrial cancer
Mefenamic acid (Ponstel)
NSAID effective for menstrual pain
hormone therapy has been approved for
trx of vasomotor symptoms, trx of atrophic vaginitis, and prevention of osteoporosis
differential diagnosis for women with lower abd pain/cramping
IBS, endometriosis, endometrial cancer, ovarian cyst, uterine fibroids, PID