Wk 4: nervous system Flashcards
Central Nervous System (CNS)
brain AND spinal cord
Peripheral Nervous System (PNS)
nerves and autonomic ganglia (part of the ANS)
Communication lines between the CNS and the rest of the body
PNS relays information from:
Internal: viscera, afferent nerves (IV)
External: sensory, afferent nerves
Sent to CNS and includes efferent responses from brain to target cells/organs (efferent).
Parasympathetic
“rest and digest”
conserves energy
Sympathetic:
“fight or flight”
mobilises body systems during activity
Somatic:
Skeletal
Types of cells in CNS
Neurons and Neuroglia
Neuroglia
specialized cells found in close association with neurons
(Don’t participate directly in information transfer)
Neurons
excitable cells that transmit a nervous message
Types of neuron cells
- Multipolar neuron (motor neuron & interneuron): most common
- Bipolar neuron (sensory neuron, eye and ear): rare
- Pseudo unipolar (sensory neuron): frequent in this neuron
Four types of glia
Oligodendrocytes
Astrocytes
Microglia
Ependymal
Oligodendrocytes
makes myelin on axons
1oligodendrocyte : 60 axons
Astrocytes
Roles
- Structural support
- Provides nutrients/homeostasis for neurons
- Maintains/regulates synaptic connections
- Reacts to injuries = astrogliosis
Microglia
resident macrophages in the brain “the brains immune cells”
increase in phagocytosis after injury results from migration of cells to the injured area
Ependymal cells
provide lining in the ventricles and help produce Cerebro-spinal Fluid (CSF)
Types of glial cells in PNS
Schwann cells
Satellite cells
Schwann cells
divide frequently, myelinate fast and are highly resistant to injury
(Similar function to oligodendrocyte)
Satellite cells
support neurons and enhance their function
(Similar function than astrocytes)
RMP
the electrical potential difference across the plasma membrane when the cell is in a non-excited state
RMP depends on
- Permeability
- Electrochemical gradients
- Presence of Na+/K+ on the neuronal membrane
Methods of propagating action potentials
- Continuous propagation (in unmyelinated axons)
- Saltatory propagation (in myelinated neurons)
Synapses
junctions between neuron/cell allowing them to communicate with one another
Types of synapses
1) Electrical: gap junction (bidirectional): very fast connection present mainly in brain and heart
2) Chemical: (unidirectional) most common ones in mammals.
Neurotransmitters
released at presynaptic membrane (exocytosis) and bind to specific receptors at the postsynaptic neuronal membrane