PART 1 ALL CONTENT Flashcards
Levels of organisation
Chemical
Cellular
Tissue
Organ
Organ system
Organsim
Body cavities
spaces that enclose internal organs
Cells
the basic structural and functional units of the body
Classes of cells
Germ and somatic
Cell membrane function
- Maintains composition of inter and extra cellular fluid
- Determines movement of substances in and out of cell
- Communicates with other cells and organs
Phospholipid consists of what two things
Hydrophilic phosphate heads (water loving)
Hydrophobic lipid tails (water hating)
Simple diffusion molecules
Small, uncharged and lipid soluble
Facilitated diffusion molecules
Large or charged or water soluble
Simple diffusion
the movement of a molecule directly through the phospholipid bilayer from high to low concentration
Factors affecting rate of simple diffusion
concentration gradient
Facilitated diffusion
the movement of an ion or molecule from high to low concentration, via a channel or carrier protein
Factors affecting rate of facilitated diffusion
concentration gradient
Osmosis
movement of water
Water is water soluble: use a channel (aquaporin) to cross membrane
Move from high to low water concentration
Active transport
the movement of a molecule from an area of low to high concentration, via a channel or carrier protein
Factors affecting rate of active transport
Availability of ATP
Exocytosis
the release of fluids and/or solids from the cell via intracellular vesicles. ATP is required
Receptor-mediated transport
Target molecules bind to receptor proteins on the membrane surface triggering vesicle formation
Pinocytosis
Vesicles form at the membrane and bring fluids and small molecules into the cell
Phagocytosis
SOLID Vesicles form at the membrane to bring solid particles into the cell
Tonicity
the capability of a solution to modify the volume of cells by altering their water content
Vesicle
Membrane enclosed sac used to take in, transport and secrete substances in & out of cell
RER
protein synthesis
SER
metabolic processes, including synthesis of lipids and steroids, metabolism of carbohydrates
Golgi Apparatus
Storage, alteration and packing of secretory products and lysosomal enzymes
Direct communication
Physical contact
Gap junction
Indirect communication
No direct contact
Requires messanger molecule
Autocrine
Messenger molecule remains in interstitial fluid and act on the same cell
Paracrine
Messenger molecule remains in interstitial fluid and act on a different cell
Neurotransmission
Secretion of a neurotransmitter by a neuron to act on target cells
Endocrine
Endocrine signal (hormone) released into bloodstream and travels to target cell
Neurocrine
Neurocrine signal (hormone) released into bloodstream and travels to target cell
Neurotransmission characteristics
Neurotransmitter
Synapses
Onset of action in miliseconds
Duration of action is short
Neurosecretion characteristics
Neurohormone
Blood
Onset of action seconds to days
Duration of action is longer