Wk 2: Surface Epithelium Flashcards
6 Functions of Epithelial Tissue
- Protection
- Transcellular transport via selective permeability of intracellular junctions between epithelial cells
- Secretion - hormones, enzymes, other molecules
- Absorption of material from lumen
- Sensation via tastebuds
- Immune defense - physical barrier prevents invasion & epithelial cells house cells of immune system
What is the epithelium separated from the underlying CT by?
By an extracellular matrix referred to as the basement membrane
since epithelium is avascular, how is nourishment supplied?
Nourishment & O2 supplied by adjacent connective tissue through capillary beds via diffusion through basement membrane.
What kind of regenerative capacity do epithelium have
High regenerative capacity & can reproduce rapidly as long as they have adequate nutrition
What are the 2 constituents of the basement membrane
- Basal Lamina
- Lamina Reticularis
Functions of basal lamina (of basement membrane)
Molecular filter & support for overlying epithelium
2 components of the basal lamina
- Lamina Lucinda
- Lamina Densa
Where is simple epithelium found
Adapted for transport of substances between tissues.
Found in areas where absorption, secretion & filtration occur.
Where is stratified epithelium found
In high abrasion areas where protection is needed
What do polarised cells possess
An apical domain that faces lumen.
A basolateral domain whose basal component is in contact w basal lamina.
What is simple squamous epithelium adapted for
- Rapid diffusion (one cell thick) of substances - O2, CO2, fluids, ions
Where is simple squamous epithelium found
- Lining air sacs of lungs
- Lining segments of kidney tubules
- Lining blood vessels
What are simple cuboidal epithelium thin enough for
Rapid diffusion of substances
Where are simple cuboidal epithelium found
- Renal tubules
- Respiratory passages
- Ducts of many glands
- Thyroid gland
Where are the nuclei located in simple columnar epithelium
Nuclei located in basal portion of cell
What do simple columnar epithelium often have on them and for what purpose
- Microvilli on apical membrane - increases surface area for absorption of substances
- Cilia - propel substances through hollow organs