Wittig Rxn Flashcards
1
Q
purpose
A
turns a carbonyl C=O into a C=C
2
Q
process
A
form yllide by reacting Ph3P with an alkyl halide
use n-BuLi as second step
react with carbonyl
3
Q
alkyl halide restrictions
A
CH3, 1º, 2º slow
4
Q
F.G compatibility in carbonyl
A
alkane, alkene, internal alkyne, cycloalkane, aromatic, ether, ester, halogens
5
Q
F.G incompatibility in carbonyl
A
acidic protons (ROH, carbox. acid)