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Organic Chemistry II > Acidic Ether Cleavage > Flashcards

Acidic Ether Cleavage Flashcards

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1
Q

purpose?

A

cleave an ether with a nucleophilic acid to form 2 alkyl halides

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2
Q

need?

A

nucleophilic acid ex. H-Br or H-I

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3
Q

best substrate?

A

1º

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4
Q

mechanism for best substrate?

A

1º goes Sn2

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5
Q

other substrates?

A

2º / 3º give Sn1 and E1 products

push 2º Sn2 by using a polar aprotic solvent

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Organic Chemistry II (56 decks)

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