Wilms Tumor Flashcards
1
Q
Most common primary renal tumor of childhood
A
Wilms tumor
2
Q
Mutation in
A
Tumor suppressor genes
WT1 and WT2
3
Q
WAGR syndrome
A
Wilms tumor
Genital anomalies
Aniridia
Mental retardation
4
Q
Gross
A
Well circumscribed unilateral
5
Q
Cut section
A
Soft
Tan to gray
Hemorrhagic
Cyst formation
Necrosis
6
Q
Three major components in microscopy
A
Blastemal component
Immature stromal component
Immature epithelial component
7
Q
What does blastemal component composed of
A
Small round to oval blue cells
Scanty cytoplasm
Arranged in nests and cords
8
Q
Clinical features
A
Abdominal mass
Hematuria
Pain
