Polyps Of Colon

Question 1

Types

Answer 1

Non neoplastic
1. Inflammatory
2. Hamartomarous
3. Hyperplastic
Neoplastic
1. Tubular adenomas
2. Villous adenomas
3. Tubulovillous adenomas

Question 2

Features of inflammatory polyps

Answer 2

Non cancerous
Found in ulcerative colitis

Question 3

Types of hamartomatous polyps

Answer 3

Juvenile polyopsis coli syndrome
Peutz jeghers syndrome

Question 4

Saw toothed appearance

Answer 4

Hyperplastic polyps

Question 5

2 types of polyposis syndrome

Answer 5

Familial adenomatous polyopsis
Hereditary non polyopsis colorectal cancer HNPCC/lynch syndrome

Question 6

Are polyposis syndrome autosomal dominant or recessive

Answer 6

Dominant

Question 7

Hundreds to thousands of Aden mas in colon & rectum seen in

Answer 7

Familial adenomatous polyposis

Question 8

Which gene is responsible for fap (familial adenomatous polyposis )

Answer 8

Adenomatous polyposis coli gene (apc )

Question 9

When extra intestinal manifestations are prominent in fap

Answer 9

Gardner syndrome ( osteomas of mandible, skull, long bones, tumors of abdomen wall , thyroid tumor )

Question 10

Turcot syndrome

Answer 10

Colonial adenomas plus CNS tumors

Question 11

Hallmark mutation in HNPCC

Answer 11

DNA repair genes MSH 1 ,2

Question 12

What happens after MSH 1,2 mutation

Answer 12

Micro satellite instability