Wilm's' tumour Flashcards
What is another term for Wilms’ tumour?
Nephroblastoma
What is a Wilms’ tumour?
Embryonic tumour from the developing kidney
What is a Wilms’ tumour a common form of?
One of the most common childhood malignancies
Who is typically affected by a Wilms’ tumour?
Children under 5
Median age of 3
What are the main presenting features of a Wilms’ tumour?
Abdominal mass that doesn’t cross the midline
Painless haematuria
Hypertension
What does the abdominal mass in someone with a Wilms’ tumour not do?
It doesn’t cross the midline
Is a wilm’s tumour usually unilateral or bilateral?
Unlateral
What is the most common metastases in someone with a Wilms’ tumour?
Metastases to the lung
When should you refer a child for a suspected Wilms’ tumour?
Unexplained enlarged abdominal mass
Paediatric review with 48 hours
What investigation is done to identify the extent and spread of the disease?
CT chest, abdomen and pelvis
What investigation is used for definitive diagnosis of a Wilms’ tumour?
Renal biopsy
What might you find on a renal biopsy of someone with a Wilms’ tumour?
Small round blue cells may be seen on histology
What is the management of a Wilms’ tumour?
Nephrectomy
Chemotherapy
When might radiotherapy be used in the management of a Wilms’ tumour?
Progressive disease
What is the prognosis of a Wilms’ tumour?
Excellent
