Staph and Strep infections Flashcards
When does staphylococcal scalded skin syndrome usually occur?
After a history of a sore throat
Who does staphylococcal scalded skin syndrome occur in?
Younger people- infants up to about 6 years old
How does staphylococcal scalded skin syndrome present
- Widespread erythroderma (>90%)
- Fluid filled blisters lead to desquamation
- Fever and irritable
- Nikolsky sign positive
- ORAL MUCOSA UNAFFECTED
What will be positive in someone with staphylococcus scalded skin syndrome?
Nikolsky sign positive
What is unaffected in staphylococcal scalded skin syndrome?
Oral mucosa is unaffected
How is staphylococcal scalded skin syndrome diagnosed?
Skin biopsy
What is the management of staphylococcal scalded skin syndrome?
IV antibiotics
What is staphylococcal toxic shock syndrome?
Severe systemic reaction to staphylococcal exotoxins
What staphylococcal exotoxin causes toxic shock syndrome?
TSST-1 superantigen toxin.
What diagnostic criteria is used for toxic shock syndrome?
Centers for Disease Control and Prevention diagnostic criteria
What is the Centers for Disease Control and Prevention diagnostic criteria fort toxic shock syndrome?
- fever: temperature > 38.9ºC
- hypotension: systolic blood pressure < 90 mmHg
- diffuse erythematous rash
- desquamation of rash, especially of the palms and soles
Where in particular would you see desquamation of the rash with toic shock syndrome?
Palms and soles of feet
How many organ systems need to be involved for the diagnosis of toxic shock syndrome?
3 or more
What organ system involvement can there be for the diagnosis of toxic shock syndrome?
- gastrointestinal (diarrhoea and vomiting)
- mucous membrane erythema
- renal failure
- hepatitis
- thrombocytopenia
- CNS involvement (e.g. confusion)
What is the initial management of toxic shock syndrome?
Removal of infection focus (e.g. retained tampon)