What cells are commonly involved in the generation of inflammation

Question 1

What is an inflammatory response?

Answer 1

Inflammation is the process by which the immune system recognises and removes harmful and foreign stimuli and begins the healing process can be either Acute or Chronic

Question 2

Acute Inflammatory response

Answer 2

An immediate response with limited specificity caused by several stimuli such as infection and tissue damage

Question 3

Chronic inflammatory response

Answer 3

Slow and long-term inflammation which can last several months or years

Question 4

How are inflammatory responses generated?

Answer 4

Generated in response to tissue injury starting with the recognition of the stimuli, release of inflammatory mediators, vasodilation and increased permeability, migration of immune cells, phagocytosis and tissue repair

Question 5

What type of cells are involved

Answer 5

Macrophages, Neutrophils, Dendritic cells T cells and B cells

Question 6

Macrophages

Answer 6

Initiate and regulate inflammation, they can recognise and engulf pathogens

Question 7

Neutrophils

Answer 7

Release antimicrobial substances to destroy pathogens

Question 8

Dendritic cells

Answer 8

Capture, process and present antigens to T cells, initiating adaptive immune response

Question 9

T cells

Answer 9

Release cytokines that regulate the activity of other immune cells and contribute to the elimination of pathogens

Question 10

B cells

Answer 10

Produce antibodies that can neutralise pathogens or tag them for destruction by other immune cells

Question 11

Direct involvement in inflammatory response

Answer 11

The cells from the innate are the first to react against stimuli and present the antigen to the cells from the adaptive so they can take over

Question 12

Indirect involvement in inflammatory response

Answer 12

Cells release biological molecules to inform other cells that there is a foreign stimulus such as platelets releasing signals that attract more immune cells