Week Six: Pathophysiology Flashcards
Canine AIHA
Autoimmune hemolytic anemia – also called immune-mediated hemolytic anemia
destruction of red blood cells (RBCs) by the dog’s own immune system
Coomb’s test tests for this
Canine rheumatoid arthritis
Immune activated destruction of synovium, cartilage, reduced lubricity of the synovial joint fluid
Feline AIDS/FIV
Sets stage for URTI, stomatitis/faucitis, ocular lesions, chronic wasting syndrome
Alters lymphocytes and macrophages
Lymphoma stages
Stage one: Involvement of a solitary lymph node or lymphoid tissue in a single organ
Stage two: Several lymph nodes in same general area involved
Stage three: All peripheral lymph nodes involved
Stage four: Involvement of liver and/or spleen, and/or anterior mediastinum in the chest involved
Stage five: Involvement of bone marrow (some classifications consider cutaneous involvement in this stage)
What is a positive control for an allergen test?
What is a negative control?
Positive: Histamine (to confirm response system is intact)
Negative: Sterile saline (how much redness is due to injection of sterile saline)
MRSA
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium that causes infections in different parts of the body
Scabies
tends to cause hair loss, bald spots, scabbing and sores
What can treat parasitic dermatopathies?
Tetracyclien class like doxycyclin
Canine histiocytomas
“Button or mushroom ulcer”
Benign tumor of young dogs- many will regress without treatment
What are canine papillomitosis?
Warts
What is the mitotic index?
a measure for the proliferation status of a cell population. It is defined as the ratio between the number of cells in mitosis and the total number of cells.
Mast Cells
cells that reside in the connective tissues, especially those vessels and nerves that are closest to the external surfaces (e.g., skin, lungs, nose, mouth). Their primary functions include defense against parasitic infestations, tissue repair, and the formation of new blood vessels (angiogenesis)
