Week 9

Question 1

Aricept

Answer 1

Brand: Aricept
Generic: donepezil
Class: acetylcholinesterase inhibitor (central)
Indication: alzheimer’s
Counseling points:
- Take in the evening prior to bedtime with or without food
- May cause significant nausea, vomiting, diarrhea, fatigue, and anorexia

Question 2

Namenda

Answer 2

Brand: Namenda
Generic: memantine
Class: NMDA receptor antagonist
Indication: alzheimer's
Counseling points: 
- May cause headache, dizziness, confusion
- Take without regarding food

Question 3

Exelon

Answer 3

Brand: Exelon
Generic: rivastigmine
Class: acetylcholinesterase inhibitor (central)
Indication: dementia from alzheimer’s or parkinson’s
Counseling points:
- May cause significant nausea, vomiting, diarrhea, and anorexia
- Oral: Should be administered with meals (breakfast or dinner); Capsule should be swallowed whole; Liquid form available for patients who cannot swallow capsules
- Patch: Rotate patch application sites daily; avoid reapplication to same spot of skin for 14 days

Question 4

Samsca

Answer 4

Brand: Samsca
Generic: tolvaptan
Class: vasopressin antagonist
Indication: hypervolemic or euvolemic hyponatremia
Counseling points:
- Report sysmptoms of osmotic demyelination syndrome or hepatic injury
- May cause thirst, dry mouth, constipation
- AVOID GRAPEFRUIT JUICE

Question 5

Mirapex

Answer 5

Brand: Mirapex
Generic: pramipexole
Class: dopamine agonist
Indication: parkinson’s, RLS
Counseling points:
- May cause nausea, hallucinations, drowsiness, and falling asleep without warning
- Titrate dose gradually to avoid intolerable side effects
- Exercise caution in operating heavy machinery
- Take with food to decrease nausea
- Report any abnormalities in vision

Question 6

Amaryl

Answer 6

Brand: Amaryl
Generic: glimepiride
Class: sulfonylurea
Indication: type 2 diabetes
Counseling points: 
- Take with breakfast
- Counsel on hypoglycemia recognition and management
- Avoid alcohol use

Question 7

Glucophage

Answer 7

Brand: Glucophage
Generic: metformin
Class: biguanide
Indication: type 2 diabetes
Counseling points: 
- Take with breakfast
- Counsel on hypoglycemia recognition and management
- Avoid alcohol use

Question 8

Actos

Answer 8

Brand: Actos
Generic: pioglitazone
Class: thiazolidinedione
Indication: type 2 diabetes
Counseling points:
- Take once daily without regarding meals
- May cause macular edema, heart failure, weight gain, and edema
- Increased risk of fractures and bladder cancer in men

Question 9

Prandin

Answer 9

Brand: Prandin
Generic: repaglinide
Class: meglitinide analog
Indication: type 2 diabetes
Counseling points:
- Take once daily without regarding meals
- May cause macular edema, heart failure, weight gain, and edema
- Increased risk of fractures and bladder cancer in men

Question 10

Avandia

Answer 10

Brand: Avandia
Generic: rosiglitazone
Class: thiazolidinedione
Indication: type 2 diabetes
Counseling points:
- Use reliable contraception (may stimulate ovulation)
- May cause fluid retention (watch heart conditions), hypoglycermia, and HA
- Effects may not take full effect for up to 3 months

Question 11

Onglyza

Answer 11

Brand: Onglyza
Generic: saxagliptin
Class: dipeptidyl peptidase 4 (DPP-4) inhibitor
Indication: type 2 diabetes
Counseling points: 
- Report symptoms of CHF 
- May cause URI/UTI 
- Counsel missed dose