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Patient Care > week 8 > Flashcards

week 8 Flashcards

1
Q

Apixaban Brand

A

Eliquis

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2
Q

Apixaban class and IND

A

Factor Xa inhibitor

Prevention of stroke in non-valvular a-fib. DVT and PE treatment, VTE prophylaxis (Total hip or knee replacement)

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3
Q

Apixaban MOA

A

Directly binds to and inhibits factor Xa which is necessary for the generation of thrombin for thrombus formation

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4
Q

Apixaban AE

A

Bleeding, nausea, elevation in liver enzymes

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5
Q

Atenolol Brand

A

Tenormin

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6
Q

Atenolol Class and iND

A

Selective Beta-1-Blocker

Angina, HTN, Myocardial Infarction
Off Label: A-fib, SVT

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7
Q

Atenolol MOA

A

Inhibits beta-1 receptors in the heart resulting in a reduction of the pulse and cardiac output that can lower the blood pressure

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8
Q

Atenolol AE

A

Bradycardia, bronchospasm, fatigue, hypotension, depression, sexual dysfunction

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9
Q

Atorvastatin brand

A

Lipitor

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10
Q

Atorvastatin Class and IND

A

Statin ( HMG-CoA Reducatase Inhibitor)

Hyperlipidemia, Familial hyperlipidemia, Primary and seconday of atherosclerotic CVD

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11
Q

Atorvastatin AE

A

Hyperglycemia, liver enzymes elevation, myalgia, myositis (elevation in CK), rhabdomyolysis

CI in pregnancy

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12
Q

Benazepril Brand

A

Lotensin

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13
Q

Benazepril class and IND

A

ACE-I

HTN >6 years old

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14
Q

Benazepril MOA

A

In the enzymes, angiotensin converting enzyme (ACE), which is needed to convert angiotensin 1 to angiotensin 2

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15
Q

Benazepril AE

A

Angioedema, cough (dry cough), hyperkalemia, worsening renal function, hypotension

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16
Q

Bisoprolol brand

A

Zebeta

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17
Q

Bisoprolol class and IND

A

Selective Beta 1 blocker

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18
Q

Bisoprolol MOA

A

The inhibition of the beta-1 receptors in the heart are known to facilitate a reduction in chronotropy and inotropy resulting in a reduction of the pulse and cardiac output that can lower the blood pressure.

Some vasoconstriction due to some degree of beta2 antagonism.

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19
Q

Bisoprolol AE

A

Bradycardia, bronchospasm, fatigue, hypotension, depression, sexual dysfunction

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20
Q

Candesartan Brand

A

Atacand

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21
Q

Candesartan class and IND

A

ARB

Heart Failure, HTN, Left ventricular dysfunction post MI
Off-Label: Angina, a fib, cardiac dysrhythmias

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22
Q

Candesartan MOA

A

Selectively antagonizes the angiotensin 2 receptor which leads to a reduction in afterload and vascular/cardiac remodeling

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23
Q

Candesartan AE

A

Angioedema, cough, hyperkalemia, worsening renal function, hypotension

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24
Q

Carvedilol Brand

A

Coreg

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25
Q

Carvedilol class and IND

A

Mixed alpha/beta blocker

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26
Q

Carvedilol MOA

A

Selectively inhibits alpha 1 mediated vascoconstrictive effects on arteries to reduce blood pressure and also function as a non-selective beta-blocker which can reduce the pulse, stroke volume, cardiac output, and vascular remodeling.

27
Q

Carvedilol AE

A

Braycardia, bronchospasm, depression, dizziness, fatigue, hypotenstion, sexual dysfunction

28
Q

Clonidine brand

A

Catapres

29
Q

Clonidine class and IND

A

Centrally acting alpha 2 agonist

ADHD, HTN
Off-Label: Acute HTN, Hot swets, Nicotine and opiod withdraw, spasticity, tourette syndrome

30
Q

Clonidine MOA

A

Functions as an agonist at the pre-synaptinc alpha 2 receptor in the CNS and results in a decreased release of NE and overall sympathetic outflow to target organs

31
Q

Clonidine AE

A

Bradycardia, constipation, fatigue, HTN and tachycardia, hypotension, sedation, xerostomia

32
Q

Dabigatran brand

A

Pradaxa

33
Q

Dabigatran class and IND

A

Anticoagulant

DVT & PE, DVT prevention after hip replacement, stroke prevention

34
Q

Dabigatran MOA

A

Reversible and direct inhibition of the thrombin which is needed in the formation of a clot and does not need the presences of antithrombin in order to work

35
Q

Dabigatran AE

A

Bleeding, dyspepsia, gastritis

36
Q

Febuxostat brand

A

Uloric

37
Q

Febuxostat class and IND

A

Xanthine Oxidase inhibitor

Hyperuricemia

38
Q

Febuxostat MOA

A

Inhibits the enzyme, xanthine oxidase, which is responsible for converting xanthine to uric acid, which is more water soluble.

39
Q

Febuxostat AE

A

Nausea, increat Liver enzymes, rash, arthralgia

40
Q

Felodipine brand

A

Plendil

41
Q

Felodipine class and IND

A

CCB (Dihydro)

42
Q

Felodipine MOA

A

Inhibits the calcium channels within the smooth muscle cells of arteries thereby reducing the cytosolic calcium concentrations that allow for contraction

43
Q

Felodipine AE

A

Constipation, reflux, peripheral and lower extremity edema, reduction in BP, reflex tachycardia

44
Q

Irbesartan brand

A

Avapro

45
Q

Irbesartan class and IND

A

ARB

Diabetic nephropathy, HTN

46
Q

Irbesartan MOA

A

Selectively antagonizes the angiotensin 2 receptor which leads to a reduction i n afterload and vascular/cardiac remodeling

47
Q

Irbesartan AE

A

Angioedema, hyperkalemia, worsening renal function, hypotension

48
Q

Isosorbide Mononitrate brand

A

Imdur

49
Q

Isosorbide Mononitrate class and IND

A

Long acting nitrate, vasodilator

Angina pectoris

50
Q

Isosorbide Mononitrate MOA

A

After being convertd to nitric oxide in the vasculature, it activated the intracellular enzyme, guanylate cyclase which then incerases cGMP mediated pathways within smooth muscle cells lining the blood vessels to reduce cystolic calcium levels that reduce actin/myosin interaction and eventually lead to vasodilation.

51
Q

Isosorbide Mononitrate AE

A

Dizziness, HA flushin, hypotension, orthostasis

52
Q

Nebivolol brand

A

Bystolic

53
Q

Nebivolol class and IND

A

Selective Beta 1 blocker

HTN

54
Q

Nebivolol MOA

A

Inhibition o f beta 1 receptors in t he heart are known to facilitate a reduction in chronotropy and inotropy resulting in a reduction of the p ulse and cardiac out that can l ower the blood pressure

55
Q

Nevivolol AE

A

Bradycardia, bronchospasm, fatigue, hypotension, depression, sexual dysfunction

56
Q

Valsartan Brand

A

Diovan

57
Q

Valsartan Class and IND

A

ARB

Heart failure, HTN, MI

58
Q

Valsartan MOA

A

Antagonizes angiotensin 2 receptor which leads to a reduction in afterload and vascular/cardiac remodeling

59
Q

Valsartan AE

A

Angioedema, cough, hyperkalemia, worsening renal function, hypotension

60
Q

Verapamil brand

A

Calan, Verelan

61
Q

Verapamil class and IND

A

NHD CCB

HTN, Angina, Atrial tachydysrhythmias

62
Q

Verapamil MOA

A

Inhibits calcium from entering into the myocardial and vascular smooth muscle via the voltage sensitive calcium channels, thereby reducing the interaction of actin and myosin.

63
Q

Verapamil AE

A

Bradycardia, constipation, dizziness, edema, fatigue, gingival hyperplasia, worsening heart failure, heart block

Patient Care (11 decks)

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