Quiz 6 Flashcards
Acyclovir brand name
Zovirax
Acyclovir class and indication
Antiviral
Genital herpes & Herpes zoster
Acyclovir MOA
Inhibits viral DNA polymerase thereby preventing viral DNA replication.
Acyclovir AE
HA, nausea, vomiting, diarrhea, malaise
Alendronate brand name
Fosamax, Binosto
Alendronate class and Ind
Oral bisphosphonate
Osteoporosis, Paget Disease
Alendronate MOA
Inhibits the ability of osteoclasts from being able to breakdown bone by forming a bond with hydroxyapatite.
Alendronate AE
Bone pain, gastritis, myalgia, osteonecrosis of jaw
Aripiprazole brand
Abilify
Aripiprazole class and ind
Atypical Antipsychotic 2nd gen
Ariprprazole MOA
Modulates the activity of D2, D2, 5-HT1A/2A Activity in the CNS. There is some partial agonist activity to D2 and 5-HT1A.
Aripiprazole AE
akathisia (feeling of restlessness), anxiety, EPS, hyperglycemia, nausea, vomiting, QT prolongation, tremor
Atomoxetine brand
Stattera
Atomoxetine clas and ind
SNRI
ADHD
Atomoxetine MOA
Selectively inhibits the reuptake of norepinephrine in the CNS that helps control symptoms associated with ADHD.
Atomxetine AE
Elevated BP, increased pulse, nausea & abdominal pain, insomnia, wt. loss, loss of appetite.
Benztropine brand
Cogentin
Benzotropine class and Ind
Anticholinergic & Anti-parkinsons
- Extrapyramidal Disease (abnormal involuntary movements, alterations in muscle tone, and postural );
- Parkinsonism
Benzotropine AE
Anhidrosis (inability to sweat), blurred vision, constipation, confusion, sedation, urinary retention, xerostomia (dry mouth)
Benzonatate brand
Tessalon Perles
Bezonatate class and IND
Antitussive
Cough
Benzonatate MOA
Cause a local anesthetic effect on the respiratory stretch receptors because it is a congener of tetracaine.
Benzonatate AE
Dizziness, HA, changes in behavior
Bupropion brand
Wellbutrin Alpenzin, Forfivo
Buproprion class and IND
Mixed dopamine/NE reuptake inhibitor, Antidepressant
Depression, Seasonal affective disorder, smoking cessation
Buproprion MOA
Mixed inhibition of the reuptake of both dopamine and norepinephrine in the CNS.
off label: ADHA, Bipolar disorder
Buproprion AE
Agitation, anxiety, confusion, dizziness, HA, hypertension, insomnia, tremors.
Carisoprodol brand
Soma
Carisoprodol class and IND
Muscle relaxant
Musculoskeletal conditions
Carisoprodol MOA
Unknown but thought to inhibit inter-neuronal activity within the spinal cord. It is also metabolized to Meprobamate, which is an agent for anxiety
Carisoprodol AE
Dizziness, drowsiness, HA
Celecoxib brand
Celebrex
Celecoxib class and IND
COX 2 inhibitor; Non-opiod analgesic
Anklosing spondylitis, Acute pain assoc. w/dysmenorrhea, Osteoarthritis, Rheumatoid Arthritis
off-label: Gout
Celecoxib MOA
Selectively inhibits Cox-2 enzymes which is necessary for conversion arachidonic acid to proinflammatory prostaglandins.
Celecoxib AE
GI effects (distress, ulcers), elevated BP, HA, Rash, Risk of MI due to edema.
Carbamazepine brand
Tegretol, Carbatrol, Epitol, Equetro
Carbamazepine class and indication
Anticonvulsant; Mood stabilizer
Bipolar Disorder (Equetro only); Epilepsy; Trigeminal neuralgia
Off Label: Neuropathic pain, Restless leg syndrome
Carbamazepine MOA
Inhibits sodium influx in the nerve and in the presynaptic nerve to decrease the release of neurotransmitters.
Carbamazepine AE
Agranulocytosis, confusion, dizziness, hyponatremia, pancreatitis, rash.
Citalopram brand
Celexa
Citalopram class and indication
SSRI; Antidepressant
Citalopram MOA
Selectively inhibits the reuptake of serotonin in the synaptic cleft.
Citalopram AE
Anxiety, agitation, dizziness, HA, impotence, insomnia, nausea, QT prolongation (dose-dependent), suicide (increased risk).
Clonazepam brand
Klonopin
Clonazepam class and IND
Benzo
IND: Panic Disorder, Seizures
Off Label: Bipolar disorder, Burning mouth syndrome, Essential tremor, Restless Leg Syndrome, Tic Disorder, Tardive dyskinesia
Dexmethylphenida brand
Focalin
Dexmethylphenida class and IND
CNS stimulant
IND: ADD, ADHD
Off Label: Augmentin of Depressive Disorder
Dexmethylphenida MOA
Mainly inibits the reuptake of dopamine and norepinephrine in the synaptic cleft of the CNS but may also increase the release dopamine and norepinephrine.
Dexmethylphenida AE
Anxiety, HA, insomnia, loss of appetite, restlessness, tachycardia, weight loss, decline in growth rate dependence.
C2 CONTROLLED
Eszopiclone brand
Lunesta
Eszopiclone class and IND
Nonbarbiturate Hypnotic
Insomnia
Eszopiclone MOA
Allosterically interacts with the GABA receptor in CNS.
Eszopiclone AE
Confusion, HA, GI effects (nausea, vomiting, diarrhea), dry mouth.
Meloxicam brand
Mobic, Vivlodex
Meloxicam class and IND
NSAID
Osteoarthritis, Rheumatoid Arthritis
Meloxicam MOA
Competitively inhibits the COX enzymes which are necessary for conversion arachidonic acid to proinflammatory prostaglandins.
Meloxicam AE
Edema, GI effects (nausea, gastritis, ulcers), rash, renal impairment, bleeding, increase in BP.
Tramadol brand
Ultram, ConZip
Tramadol class and IND
Opiod
Pain management
Tramadol MOA
Tramadol has 2 mechanisms:
- ) mu opioid receptor agonist (i.e. opioid analgesic)
- ) Inhibitor of reuptake of both norepinephrine & serotonin.
Tramadol AE
Constipation, dry mouth, HA, orthostasis, sedation, pruritus