Quiz 6 Flashcards

1
Q

Acyclovir brand name

A

Zovirax

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2
Q

Acyclovir class and indication

A

Antiviral

Genital herpes & Herpes zoster

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3
Q

Acyclovir MOA

A

Inhibits viral DNA polymerase thereby preventing viral DNA replication.

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4
Q

Acyclovir AE

A

HA, nausea, vomiting, diarrhea, malaise

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5
Q

Alendronate brand name

A

Fosamax, Binosto

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6
Q

Alendronate class and Ind

A

Oral bisphosphonate

Osteoporosis, Paget Disease

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7
Q

Alendronate MOA

A

Inhibits the ability of osteoclasts from being able to breakdown bone by forming a bond with hydroxyapatite.

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8
Q

Alendronate AE

A

Bone pain, gastritis, myalgia, osteonecrosis of jaw

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9
Q

Aripiprazole brand

A

Abilify

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10
Q

Aripiprazole class and ind

A

Atypical Antipsychotic 2nd gen

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11
Q

Ariprprazole MOA

A

Modulates the activity of D2, D2, 5-HT1A/2A Activity in the CNS. There is some partial agonist activity to D2 and 5-HT1A.

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12
Q

Aripiprazole AE

A

akathisia (feeling of restlessness), anxiety, EPS, hyperglycemia, nausea, vomiting, QT prolongation, tremor

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13
Q

Atomoxetine brand

A

Stattera

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14
Q

Atomoxetine clas and ind

A

SNRI

ADHD

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15
Q

Atomoxetine MOA

A

Selectively inhibits the reuptake of norepinephrine in the CNS that helps control symptoms associated with ADHD.

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16
Q

Atomxetine AE

A

Elevated BP, increased pulse, nausea & abdominal pain, insomnia, wt. loss, loss of appetite.

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17
Q

Benztropine brand

A

Cogentin

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18
Q

Benzotropine class and Ind

A

Anticholinergic & Anti-parkinsons

  • Extrapyramidal Disease (abnormal involuntary movements, alterations in muscle tone, and postural );
  • Parkinsonism
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19
Q

Benzotropine AE

A

Anhidrosis (inability to sweat), blurred vision, constipation, confusion, sedation, urinary retention, xerostomia (dry mouth)

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20
Q

Benzonatate brand

A

Tessalon Perles

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21
Q

Bezonatate class and IND

A

Antitussive

Cough

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22
Q

Benzonatate MOA

A

Cause a local anesthetic effect on the respiratory stretch receptors because it is a congener of tetracaine.

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23
Q

Benzonatate AE

A

Dizziness, HA, changes in behavior

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24
Q

Bupropion brand

A

Wellbutrin Alpenzin, Forfivo

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25
Buproprion class and IND
Mixed dopamine/NE reuptake inhibitor, Antidepressant Depression, Seasonal affective disorder, smoking cessation
26
Buproprion MOA
Mixed inhibition of the reuptake of both dopamine and norepinephrine in the CNS. off label: ADHA, Bipolar disorder
27
Buproprion AE
Agitation, anxiety, confusion, dizziness, HA, hypertension, insomnia, tremors.
28
Carisoprodol brand
Soma
29
Carisoprodol class and IND
Muscle relaxant Musculoskeletal conditions
30
Carisoprodol MOA
Unknown but thought to inhibit inter-neuronal activity within the spinal cord. It is also metabolized to Meprobamate, which is an agent for anxiety
31
Carisoprodol AE
Dizziness, drowsiness, HA
32
Celecoxib brand
Celebrex
33
Celecoxib class and IND
COX 2 inhibitor; Non-opiod analgesic Anklosing spondylitis, Acute pain assoc. w/dysmenorrhea, Osteoarthritis, Rheumatoid Arthritis off-label: Gout
34
Celecoxib MOA
Selectively inhibits Cox-2 enzymes which is necessary for conversion arachidonic acid to proinflammatory prostaglandins.
35
Celecoxib AE
GI effects (distress, ulcers), elevated BP, HA, Rash, Risk of MI due to edema.
36
Carbamazepine brand
Tegretol, Carbatrol, Epitol, Equetro
37
Carbamazepine class and indication
Anticonvulsant; Mood stabilizer Bipolar Disorder (Equetro only); Epilepsy; Trigeminal neuralgia Off Label: Neuropathic pain, Restless leg syndrome
38
Carbamazepine MOA
Inhibits sodium influx in the nerve and in the presynaptic nerve to decrease the release of neurotransmitters.
39
Carbamazepine AE
Agranulocytosis, confusion, dizziness, hyponatremia, pancreatitis, rash.
40
Citalopram brand
Celexa
41
Citalopram class and indication
SSRI; Antidepressant
42
Citalopram MOA
Selectively inhibits the reuptake of serotonin in the synaptic cleft.
43
Citalopram AE
Anxiety, agitation, dizziness, HA, impotence, insomnia, nausea, QT prolongation (dose-dependent), suicide (increased risk).
44
Clonazepam brand
Klonopin
45
Clonazepam class and IND
Benzo IND: Panic Disorder, Seizures Off Label: Bipolar disorder, Burning mouth syndrome, Essential tremor, Restless Leg Syndrome, Tic Disorder, Tardive dyskinesia
46
Dexmethylphenida brand
Focalin
47
Dexmethylphenida class and IND
CNS stimulant IND: ADD, ADHD Off Label: Augmentin of Depressive Disorder
48
Dexmethylphenida MOA
Mainly inibits the reuptake of dopamine and norepinephrine in the synaptic cleft of the CNS but may also increase the release dopamine and norepinephrine.
49
Dexmethylphenida AE
Anxiety, HA, insomnia, loss of appetite, restlessness, tachycardia, weight loss, decline in growth rate dependence. C2 CONTROLLED
50
Eszopiclone brand
Lunesta
51
Eszopiclone class and IND
Nonbarbiturate Hypnotic Insomnia
52
Eszopiclone MOA
Allosterically interacts with the GABA receptor in CNS.
53
Eszopiclone AE
Confusion, HA, GI effects (nausea, vomiting, diarrhea), dry mouth.
54
Meloxicam brand
Mobic, Vivlodex
55
Meloxicam class and IND
NSAID Osteoarthritis, Rheumatoid Arthritis
56
Meloxicam MOA
Competitively inhibits the COX enzymes which are necessary for conversion arachidonic acid to proinflammatory prostaglandins.
57
Meloxicam AE
Edema, GI effects (nausea, gastritis, ulcers), rash, renal impairment, bleeding, increase in BP.
58
Tramadol brand
Ultram, ConZip
59
Tramadol class and IND
Opiod Pain management
60
Tramadol MOA
Tramadol has 2 mechanisms: 1. ) mu opioid receptor agonist (i.e. opioid analgesic) 2. ) Inhibitor of reuptake of both norepinephrine & serotonin.
61
Tramadol AE
Constipation, dry mouth, HA, orthostasis, sedation, pruritus