Quiz 6 Flashcards

1
Q

Acyclovir brand name

A

Zovirax

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2
Q

Acyclovir class and indication

A

Antiviral

Genital herpes & Herpes zoster

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3
Q

Acyclovir MOA

A

Inhibits viral DNA polymerase thereby preventing viral DNA replication.

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4
Q

Acyclovir AE

A

HA, nausea, vomiting, diarrhea, malaise

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5
Q

Alendronate brand name

A

Fosamax, Binosto

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6
Q

Alendronate class and Ind

A

Oral bisphosphonate

Osteoporosis, Paget Disease

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7
Q

Alendronate MOA

A

Inhibits the ability of osteoclasts from being able to breakdown bone by forming a bond with hydroxyapatite.

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8
Q

Alendronate AE

A

Bone pain, gastritis, myalgia, osteonecrosis of jaw

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9
Q

Aripiprazole brand

A

Abilify

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10
Q

Aripiprazole class and ind

A

Atypical Antipsychotic 2nd gen

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11
Q

Ariprprazole MOA

A

Modulates the activity of D2, D2, 5-HT1A/2A Activity in the CNS. There is some partial agonist activity to D2 and 5-HT1A.

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12
Q

Aripiprazole AE

A

akathisia (feeling of restlessness), anxiety, EPS, hyperglycemia, nausea, vomiting, QT prolongation, tremor

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13
Q

Atomoxetine brand

A

Stattera

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14
Q

Atomoxetine clas and ind

A

SNRI

ADHD

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15
Q

Atomoxetine MOA

A

Selectively inhibits the reuptake of norepinephrine in the CNS that helps control symptoms associated with ADHD.

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16
Q

Atomxetine AE

A

Elevated BP, increased pulse, nausea & abdominal pain, insomnia, wt. loss, loss of appetite.

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17
Q

Benztropine brand

A

Cogentin

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18
Q

Benzotropine class and Ind

A

Anticholinergic & Anti-parkinsons

  • Extrapyramidal Disease (abnormal involuntary movements, alterations in muscle tone, and postural );
  • Parkinsonism
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19
Q

Benzotropine AE

A

Anhidrosis (inability to sweat), blurred vision, constipation, confusion, sedation, urinary retention, xerostomia (dry mouth)

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20
Q

Benzonatate brand

A

Tessalon Perles

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21
Q

Bezonatate class and IND

A

Antitussive

Cough

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22
Q

Benzonatate MOA

A

Cause a local anesthetic effect on the respiratory stretch receptors because it is a congener of tetracaine.

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23
Q

Benzonatate AE

A

Dizziness, HA, changes in behavior

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24
Q

Bupropion brand

A

Wellbutrin Alpenzin, Forfivo

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25
Q

Buproprion class and IND

A

Mixed dopamine/NE reuptake inhibitor, Antidepressant

Depression, Seasonal affective disorder, smoking cessation

26
Q

Buproprion MOA

A

Mixed inhibition of the reuptake of both dopamine and norepinephrine in the CNS.

off label: ADHA, Bipolar disorder

27
Q

Buproprion AE

A

Agitation, anxiety, confusion, dizziness, HA, hypertension, insomnia, tremors.

28
Q

Carisoprodol brand

A

Soma

29
Q

Carisoprodol class and IND

A

Muscle relaxant

Musculoskeletal conditions

30
Q

Carisoprodol MOA

A

Unknown but thought to inhibit inter-neuronal activity within the spinal cord. It is also metabolized to Meprobamate, which is an agent for anxiety

31
Q

Carisoprodol AE

A

Dizziness, drowsiness, HA

32
Q

Celecoxib brand

A

Celebrex

33
Q

Celecoxib class and IND

A

COX 2 inhibitor; Non-opiod analgesic

Anklosing spondylitis, Acute pain assoc. w/dysmenorrhea, Osteoarthritis, Rheumatoid Arthritis

off-label: Gout

34
Q

Celecoxib MOA

A

Selectively inhibits Cox-2 enzymes which is necessary for conversion arachidonic acid to proinflammatory prostaglandins.

35
Q

Celecoxib AE

A

GI effects (distress, ulcers), elevated BP, HA, Rash, Risk of MI due to edema.

36
Q

Carbamazepine brand

A

Tegretol, Carbatrol, Epitol, Equetro

37
Q

Carbamazepine class and indication

A

Anticonvulsant; Mood stabilizer

Bipolar Disorder (Equetro only); Epilepsy; Trigeminal neuralgia

Off Label: Neuropathic pain, Restless leg syndrome

38
Q

Carbamazepine MOA

A

Inhibits sodium influx in the nerve and in the presynaptic nerve to decrease the release of neurotransmitters.

39
Q

Carbamazepine AE

A

Agranulocytosis, confusion, dizziness, hyponatremia, pancreatitis, rash.

40
Q

Citalopram brand

A

Celexa

41
Q

Citalopram class and indication

A

SSRI; Antidepressant

42
Q

Citalopram MOA

A

Selectively inhibits the reuptake of serotonin in the synaptic cleft.

43
Q

Citalopram AE

A

Anxiety, agitation, dizziness, HA, impotence, insomnia, nausea, QT prolongation (dose-dependent), suicide (increased risk).

44
Q

Clonazepam brand

A

Klonopin

45
Q

Clonazepam class and IND

A

Benzo

IND: Panic Disorder, Seizures

Off Label: Bipolar disorder, Burning mouth syndrome, Essential tremor, Restless Leg Syndrome, Tic Disorder, Tardive dyskinesia

46
Q

Dexmethylphenida brand

A

Focalin

47
Q

Dexmethylphenida class and IND

A

CNS stimulant

IND: ADD, ADHD

Off Label: Augmentin of Depressive Disorder

48
Q

Dexmethylphenida MOA

A

Mainly inibits the reuptake of dopamine and norepinephrine in the synaptic cleft of the CNS but may also increase the release dopamine and norepinephrine.

49
Q

Dexmethylphenida AE

A

Anxiety, HA, insomnia, loss of appetite, restlessness, tachycardia, weight loss, decline in growth rate dependence.

C2 CONTROLLED

50
Q

Eszopiclone brand

A

Lunesta

51
Q

Eszopiclone class and IND

A

Nonbarbiturate Hypnotic

Insomnia

52
Q

Eszopiclone MOA

A

Allosterically interacts with the GABA receptor in CNS.

53
Q

Eszopiclone AE

A

Confusion, HA, GI effects (nausea, vomiting, diarrhea), dry mouth.

54
Q

Meloxicam brand

A

Mobic, Vivlodex

55
Q

Meloxicam class and IND

A

NSAID

Osteoarthritis, Rheumatoid Arthritis

56
Q

Meloxicam MOA

A

Competitively inhibits the COX enzymes which are necessary for conversion arachidonic acid to proinflammatory prostaglandins.

57
Q

Meloxicam AE

A

Edema, GI effects (nausea, gastritis, ulcers), rash, renal impairment, bleeding, increase in BP.

58
Q

Tramadol brand

A

Ultram, ConZip

59
Q

Tramadol class and IND

A

Opiod

Pain management

60
Q

Tramadol MOA

A

Tramadol has 2 mechanisms:

  1. ) mu opioid receptor agonist (i.e. opioid analgesic)
  2. ) Inhibitor of reuptake of both norepinephrine & serotonin.
61
Q

Tramadol AE

A

Constipation, dry mouth, HA, orthostasis, sedation, pruritus