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Quiz 7 Diabetes Flashcards

1
Q

Colesevelam brand

A

Welchol

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2
Q

Colesevelam Class and ind

A

Bile Acid Sequestrant

Hyperlipidemia (primary prevention);
Familial hyperlipidemia (heterozygous); Type 2 diabetes
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3
Q

Colesevelam MOA

A

Binds to bile acids (that is made from
cholesterol in liver) in the lumen of the small intestine and prevents their reabsorption and recirculation back to liver. This reduction in bile
acids causes the liver to extract more
cholesterol out of circulation to make more bile acid

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4
Q

Colesevelam AE

A

Constipation, nausea, hypertriglyceridemia

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5
Q

Glimepiride brand

A

Amaryl

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6
Q

Glimepiride class and ind

A

Sulfonylurea; Secretagogue; Antidiabetic
Agent

Type 2 DM

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7
Q

Glimepiride MOA

A

Lower blood glucose levels by
increasing the secretion of insulin from betaislet
cells of the pancreas.

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8
Q

Glimepiride AE

A

hypoglycemia, dizziness, nausea,

hemolytic anemia in patients with G6PD

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9
Q

Hep A Vaccine Brand

A

Havrix, Vaqta

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10
Q

Hep A Vaccine class and indication

A

Inactivated Viral vaccine

Prevent Hep A infection

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11
Q

Hep A Vax MOA

A

Promotes antibody production (or active

immunity) against Hepatitis A infection.

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12
Q

Hep A Vax AE

A

Irritation at injection site such as redness and

soreness, HA, Fever, nausea, malaise

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13
Q

Hep B Vax Brand

A

Engerix-B, Recombivax HB

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14
Q

Hep B Class and Ind

A

Inactivated viralvaccine

Prevent Hep B

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15
Q

Hep B MOA

A

Promotes antibody production (or active

immunity) against Hepatitis B infection.

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16
Q

Hep B Vax AE

A

Irritation at injection site such as redness and

soreness, HA, Fever, nausea, malaise

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17
Q

HPV Vax brand

A

Gardasil

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18
Q

HPV Vax class and ind

A

Inactivated viral vaccine

Prevention of HPV infection related
precancerous lesion involving the cervix,
vagina, anus, and genital warts.

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19
Q

HPV vax MOA

A

Promotes antibody production (or
active immunity) against HPV types 6, 11, 16,
18 with Gardasil or 6, 11, 16, 18, 31, 33, 45, 52,
and 58 with Gardasil 9.

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20
Q

HPV Vax AE

A

Irritation at injection site such as redness

and soreness, HA, Fever, nausea, malaise.

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21
Q

Inhaled Insulin brand

A

Afreeza

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22
Q

Inhaled insulin class and ind

A

short acting insulin

Typ 1 or 2 DM

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23
Q

Inhaled Insulin MOA

A

Promotes the movement or uptake of
glucose from circulation into into the cell so
that glycolysis and ATP formation can occur
or shift the glucose to a glycogen or
triglycerides.

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24
Q

Inhaled insulin AE

A

hypoglycemia, sweating, diaphoresis,
tremors, dizziness, confusion, bronchospasm
(with inhalation insulin-Afreeza), wt. gain.

25
Insulin Aspart brand
Novolog
26
Insulin aspart class and ind
Rapid acting insulin Type 1 or 2 DM
27
Insulin Aspart MOA
Promotes the movement or uptake of glucose from circulation into into the cell so that glycolysis and ATP formation can occur or shift the glucose to a glycogen or triglycerides.
28
Insulin Aspart AE
Hypoglycemia, sweating or diaphoresis, | tremors, dizziness, confusion, wt. gain.
29
Insulin Detemir Brand
Levemir
30
Insulin Detemir class
Long acting insulin
31
Insulin Lispro brand
Humalog
32
Linagliptin brand
Tradjenta
33
Linagliption class and ind
DPP4-Inhibitor Type 2 DM
34
Linaglipton MOA
Inhibits the enzyme DPP4 (dipeptidyl peptidase-4) which then causes incretin levels to remain around longer and help regulate glucose metabolism.
35
Linaglipton AE
Hypoglycemia (if used with SU or insulin), | HA, wt. gain, pancreatitis
36
Liraglutide brand
Victoza, Saxenda
37
Liraglutide class and INd
GLP 1 agonist Type 2 DM
38
Liraglutide MOA
Improves the mechanism of glucose dependent insulin release from the pancreas while also decreasing glucagon secretion, increases beta-islet growth to improve glucose control.
39
Liraglutide AE
Hypoglycemia, GI: (N/V/D), dizziness, hyperbilirubinemia, injection site reactions, pancreatitis
40
Metformin Brand
Glucophage
41
Metformin Class and Ind
Biguanide IND: Type 2 Diabetes Mellitus, PCOS Off Label IND: Antipsychotic induced weight gain
42
Metformin MOA
Reduces hepato-gluconegogensis (hepatic glucose production) and enhances utilization of glucose by muscle.
43
Metformin AE
GI (N/V/D), flatulence, indigestion, weight | loss, lactic acidosis
44
Pioglitazone brand
Actos
45
Pioglitazone class and ind
TZDs Type 2 DM
46
Pioglitazone MOA
Binds to peroxisome proliferator activated receptor-gamma which regulate genes for glucose and lipid metabolism and thereby improve insulin-dependent glucose disposal in cells and reducing hepatic glucose production; Improves the target cells response to insulin w/o increasing insulin production. "Insulin Sensitizers"
47
Pioglitazone AE
Edema, wt. gain (from fluid accumulation), edema that can worsen heart failure, bone fractures, anemia (dilution from extra fluid).
48
Repaglinide brand
Prandin
49
Repaglinide class and ind
Meglutinide Type 2 DM
50
Repaglinide MOA
Stimulates the release of insulin from the pancreas by inhibition of ATP-dependent K+ channels on the beta islet cells causing influx of K+ into the cell.
51
Repaglinide AE
hypoglycemia, arthralgia, HA, GI: (N/V)
52
Rosiglitazone brand
Avandia
53
Rosiglitazone class and ind
TZD Type 2 DM
54
Rosiglitazone MOA
Binds to peroxisome proliferator activated receptor-gamma which regulate genes for glucose and lipid metabolism and thereby improve insulin-dependent glucose disposal in cells and reducing hepatic glucose production; Improves the target cells response to insulin w/o increasing insulin production. "Insulin Sensitizers"
55
Rosiglitazone AE
Edema, wt. gain (from fluid accumulation), edema that can worsen heart failure, bone fractures, anemia (dilution from extra fluid).
56
Saxagliptin brand
Onglyza
57
Saxagliptin class and ind
DPP4 inhibitor Type 2 DM
58
Saxagliptin MOA
Inhibits the enzyme DPP4 (dipeptidyl peptidase-4) which then causes incretin levels to remain around longer and help regulate glucose metabolism.
59
Saxagliptin AE
Hypoglycemia (if used with SU or insulin), | HA, wt. gain, pancreatitis

Patient Care (11 decks)

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