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Patient Care > Quiz 7 Diabetes > Flashcards

Quiz 7 Diabetes Flashcards

1
Q

Colesevelam brand

A

Welchol

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2
Q

Colesevelam Class and ind

A

Bile Acid Sequestrant

Hyperlipidemia (primary prevention);
Familial hyperlipidemia (heterozygous); Type 2 diabetes
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3
Q

Colesevelam MOA

A

Binds to bile acids (that is made from
cholesterol in liver) in the lumen of the small intestine and prevents their reabsorption and recirculation back to liver. This reduction in bile
acids causes the liver to extract more
cholesterol out of circulation to make more bile acid

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4
Q

Colesevelam AE

A

Constipation, nausea, hypertriglyceridemia

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5
Q

Glimepiride brand

A

Amaryl

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6
Q

Glimepiride class and ind

A

Sulfonylurea; Secretagogue; Antidiabetic
Agent

Type 2 DM

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7
Q

Glimepiride MOA

A

Lower blood glucose levels by
increasing the secretion of insulin from betaislet
cells of the pancreas.

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8
Q

Glimepiride AE

A

hypoglycemia, dizziness, nausea,

hemolytic anemia in patients with G6PD

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9
Q

Hep A Vaccine Brand

A

Havrix, Vaqta

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10
Q

Hep A Vaccine class and indication

A

Inactivated Viral vaccine

Prevent Hep A infection

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11
Q

Hep A Vax MOA

A

Promotes antibody production (or active

immunity) against Hepatitis A infection.

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12
Q

Hep A Vax AE

A

Irritation at injection site such as redness and

soreness, HA, Fever, nausea, malaise

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13
Q

Hep B Vax Brand

A

Engerix-B, Recombivax HB

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14
Q

Hep B Class and Ind

A

Inactivated viralvaccine

Prevent Hep B

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15
Q

Hep B MOA

A

Promotes antibody production (or active

immunity) against Hepatitis B infection.

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16
Q

Hep B Vax AE

A

Irritation at injection site such as redness and

soreness, HA, Fever, nausea, malaise

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17
Q

HPV Vax brand

A

Gardasil

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18
Q

HPV Vax class and ind

A

Inactivated viral vaccine

Prevention of HPV infection related
precancerous lesion involving the cervix,
vagina, anus, and genital warts.

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19
Q

HPV vax MOA

A

Promotes antibody production (or
active immunity) against HPV types 6, 11, 16,
18 with Gardasil or 6, 11, 16, 18, 31, 33, 45, 52,
and 58 with Gardasil 9.

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20
Q

HPV Vax AE

A

Irritation at injection site such as redness

and soreness, HA, Fever, nausea, malaise.

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21
Q

Inhaled Insulin brand

A

Afreeza

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22
Q

Inhaled insulin class and ind

A

short acting insulin

Typ 1 or 2 DM

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23
Q

Inhaled Insulin MOA

A

Promotes the movement or uptake of
glucose from circulation into into the cell so
that glycolysis and ATP formation can occur
or shift the glucose to a glycogen or
triglycerides.

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24
Q

Inhaled insulin AE

A

hypoglycemia, sweating, diaphoresis,
tremors, dizziness, confusion, bronchospasm
(with inhalation insulin-Afreeza), wt. gain.

25
Q

Insulin Aspart brand

A

Novolog

26
Q

Insulin aspart class and ind

A

Rapid acting insulin

Type 1 or 2 DM

27
Q

Insulin Aspart MOA

A

Promotes the movement or uptake of glucose
from circulation into into the cell so that glycolysis
and ATP formation can occur or shift the glucose to
a glycogen or triglycerides.

28
Q

Insulin Aspart AE

A

Hypoglycemia, sweating or diaphoresis,

tremors, dizziness, confusion, wt. gain.

29
Q

Insulin Detemir Brand

A

Levemir

30
Q

Insulin Detemir class

A

Long acting insulin

31
Q

Insulin Lispro brand

A

Humalog

32
Q

Linagliptin brand

A

Tradjenta

33
Q

Linagliption class and ind

A

DPP4-Inhibitor

Type 2 DM

34
Q

Linaglipton MOA

A

Inhibits the enzyme DPP4 (dipeptidyl
peptidase-4) which then causes incretin levels to
remain around longer and help regulate glucose
metabolism.

35
Q

Linaglipton AE

A

Hypoglycemia (if used with SU or insulin),

HA, wt. gain, pancreatitis

36
Q

Liraglutide brand

A

Victoza, Saxenda

37
Q

Liraglutide class and INd

A

GLP 1 agonist

Type 2 DM

38
Q

Liraglutide MOA

A

Improves the mechanism of glucose
dependent insulin release from the pancreas
while also decreasing glucagon secretion,
increases beta-islet growth to improve glucose
control.

39
Q

Liraglutide AE

A

Hypoglycemia, GI: (N/V/D), dizziness,
hyperbilirubinemia, injection site reactions,
pancreatitis

40
Q

Metformin Brand

A

Glucophage

41
Q

Metformin Class and Ind

A

Biguanide

IND: Type 2 Diabetes Mellitus, PCOS
Off Label IND: Antipsychotic induced weight
gain

42
Q

Metformin MOA

A

Reduces hepato-gluconegogensis
(hepatic glucose production) and enhances
utilization of glucose by muscle.

43
Q

Metformin AE

A

GI (N/V/D), flatulence, indigestion, weight

loss, lactic acidosis

44
Q

Pioglitazone brand

A

Actos

45
Q

Pioglitazone class and ind

A

TZDs

Type 2 DM

46
Q

Pioglitazone MOA

A

Binds to peroxisome proliferator
activated receptor-gamma which regulate
genes for glucose and lipid metabolism and
thereby improve insulin-dependent glucose
disposal in cells and reducing hepatic glucose
production; Improves the target cells response
to insulin w/o increasing insulin production.
“Insulin Sensitizers”

47
Q

Pioglitazone AE

A

Edema, wt. gain (from fluid accumulation),
edema that can worsen heart failure, bone
fractures, anemia (dilution from extra fluid).

48
Q

Repaglinide brand

A

Prandin

49
Q

Repaglinide class and ind

A

Meglutinide

Type 2 DM

50
Q

Repaglinide MOA

A

Stimulates the release of insulin from
the pancreas by inhibition of ATP-dependent
K+ channels on the beta islet cells causing
influx of K+ into the cell.

51
Q

Repaglinide AE

A

hypoglycemia, arthralgia, HA, GI: (N/V)

52
Q

Rosiglitazone brand

A

Avandia

53
Q

Rosiglitazone class and ind

A

TZD

Type 2 DM

54
Q

Rosiglitazone MOA

A

Binds to peroxisome proliferator
activated receptor-gamma which regulate
genes for glucose and lipid metabolism and
thereby improve insulin-dependent glucose
disposal in cells and reducing hepatic
glucose production; Improves the target cells
response to insulin w/o increasing insulin
production. “Insulin Sensitizers”

55
Q

Rosiglitazone AE

A

Edema, wt. gain (from fluid accumulation),
edema that can worsen heart failure, bone
fractures, anemia (dilution from extra fluid).

56
Q

Saxagliptin brand

A

Onglyza

57
Q

Saxagliptin class and ind

A

DPP4 inhibitor

Type 2 DM

58
Q

Saxagliptin MOA

A

Inhibits the enzyme DPP4 (dipeptidyl
peptidase-4) which then causes incretin levels to
remain around longer and help regulate glucose
metabolism.

59
Q

Saxagliptin AE

A

Hypoglycemia (if used with SU or insulin),

HA, wt. gain, pancreatitis

Patient Care (11 decks)

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