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Patient Care > Interactions and Toxicity > Flashcards

Interactions and Toxicity Flashcards

1
Q

Zolpidem

A

Ambien

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2
Q

Zolpidem Class & Indication

A

Hypnotic Agent, Control 4

-Insomnia

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3
Q

Zolpidem MOA

A

Modulates the activity of the GABA receptor whil not being structurally similar to benzodiazepine to reduce neuronal activity in the CNS.

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4
Q

Zolpidem AE

A

Blurry vision, confusion, drowsiness, headache, impaired motor coordination, somnolence.

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5
Q

Varenicline

A

Chantix

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6
Q

Varenicline Class & Inidcation

A

Partial Nicotine Agent

Smoking Cessation

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7
Q

Varenicline MOA

A

Selective agonist of the nicotine receptor in the CNS.

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8
Q

Varenicline AE

A

Constipation, dream disorder, flatulence, suicidal thoughts, sleep walking

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9
Q

Tolterodine

A

Detrol

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10
Q

Tolterodine Class & Indication

A

Urinary Antispasmodic (Anticholinergic Agent)

-Overactive bladder or dyfunctional bladder

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11
Q

Tolterodine MOA

A

Competitively binds to and antagonizes muscarinic receptors n the smooth muscle of the urinary bladder.

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12
Q

Tolterodine AE

A

Constipation, dry mouth, blurry vision, urinary retention, dizziness, increase in pulse

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13
Q

Tizanidine

A

Zanaflex

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14
Q

Tizanidine Class & Indication

A

Centrally Acting Skeletal Muscle Relaxant

Muscle Spasms

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15
Q

Tizanidine MOA

A

Functions as an agonist to the alpa-2 receptor in the CNS which increases the presynaptic inhibition that decreases spasticity but without significant reductions in blood pressure like with other alpha-2 agonists.

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16
Q

Tizanidine AE

A

Dry mouth,dizziness, depression, mild reductions in blood pressure, musclce weakness, somnolence

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17
Q

Ropinirole

A

Requip

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18
Q

Ropinirole Class & indication

A

Dopamine Agonist

Parkinson’s disease, Restless leg syndrome

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19
Q

Ropinirole MOA

A

Acts as an agonist to the D3 most but also D2 and D4 receptors in the CNS.

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20
Q

Ropinirole AE

A

Dizziness, dyskinesia (uncontrollable and voluntary muscle movement), edema, hypotension, hallucination, GI, nausea, vomiting.

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21
Q

Prochlorperazine

A

Compazine

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22
Q

Prochlorperazine Class & indication

A

Antiemetic; 1st Gen. (Typical) Antipsychotic; Phenothiazine Derivative

23
Q

Propchlorperazine MOA

A

Antagonizes the D2 receptor in the CNS.

24
Q

Propchlorperazine AE

A

Drowsiness, fatigue, headache, neuroleptic malignant syndrome, QT prolongation, seizures.

25
Q

Phenytoin

A

Dilantin

26
Q

Phenytoin Class & Indications

A

Anticonvulsant

Seizures

27
Q

Phenytoin MOA

A

Inhibits sodium channels and some calcium channels in nerves of the CNS therby inhibiting synaptic post-tetanic potentiation and propagation of electric discharge.

28
Q

Phenytoin AE

A

Gingival hyperplasia, ataxia, confusion, dizziness, hypertrichosis, tremor, rash.

29
Q

Oxybutinin

A

Ditropan

Oxytrol for women OTC

30
Q

Oxybutinin Class & Indication

A

Urinary Antispasmodic Agent (Anticholinergic)

Overactive Bladder

31
Q

Oxybutinin AE

A

Blurry vision, constipation, dizziness, dry mouth, urinary retention.

32
Q

Olanzapine

A

Zyprexa

33
Q

Olanzapine class & indication

A

2nd gen. Antagonist Antipsychotic

Acute agitation from schizophrenia or bipolar mania; Bipolar disorder; Depression; Irritability from Autistic disorder; Schizophrenia; Tourette disorder.

34
Q

Olanzapine MOA

A

Antagonist to the D2 and 5-HT2 receptors in the CNS.

35
Q

Olanzapine AE

A

akathisia, dizziness, EPS, hyperlipidemia, hyperglycemia, nausea, vomiting, hyperprolactinemia, increased appetite, QT prolongation, somnolence, tremor, weight gain.

36
Q

Methocarbamol

A

Robaxin

37
Q

Methocarbamol class & indication

A

Centrally Acting Skeletal Muscle Relaxant

Musculoskeletal pain or spasms.

38
Q

Methocarbamol AE

A

Confusion, dizziness, flushing, headache, nausea, vomiting, hemolytic anemia, jaundice, nystagmus (involuntary eye movement which causes vision blurred), rash, urticaria (hives), vertigo.

39
Q

Hydroxychloroquine

A

Plaquinel

40
Q

Hydroxychloroquine class & indication

A

Antimalarial Agent; Aminoquinoline

Lupus erythematosus; Malaria (acute and chemoprphylaxis); Rheumatoid arthritis.

41
Q

Hydroxychloroquine AE

A

Abdominal pain, dizziness, headache, vision changes, retinopathy.

42
Q

Hydroxyzine

A

Atarax, Vistaril

43
Q

Hydroxyzine class & indication

A

1st Gen. Histamine-1 Receptor Antagonist; Antiemetic; Piperazine Derivative

Uses: Anxiety, Antiemetic, Pruritis, Sedation

Off Label: Seasonal Allergitis Rhinitis

44
Q

Hydroxychloroquine MOA

A

The exact mechanism of action is unclear but thought to interfere with digestive vacuole activity within parasites.

45
Q

Finasteride

A

Propecia, Proscar

46
Q

Finasteride class & indication

A

5-Alpha Reductase Inhibitor

BPH, Alopecia (males)

47
Q

Finasteride AE

A

Dizziness, gynecomastia, impotence, reduced libido

48
Q

Hydralazine

A

Apresoline

49
Q

Hydralazine class & indication

A

Vasodilator- Antihypertensive Agent

HTN

50
Q

Hydralazine AE

A

Dizziness, headache, hypotension, palpitations, reflex tachycardia, liver damage, drug-induced SLE(DILE)

51
Q

Levetiracetam

A

Keppra

52
Q

Levetiracetam class & indication

A

Anticonvulsant

Myoclonic seizure; Partial seizure; Tonic-clonic seizure.

53
Q

Levetiracetam MOA

A

Unclear mechanism

54
Q

Levetiracetam AE

A

Agitation, depression, dizziness, fatigue, mood swings, somnolence.

Patient Care (11 decks)

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