Interactions and Toxicity

Question 1

Zolpidem

Answer 1

Ambien

Question 2

Zolpidem Class & Indication

Answer 2

Hypnotic Agent, Control 4

-Insomnia

Question 3

Zolpidem MOA

Answer 3

Modulates the activity of the GABA receptor whil not being structurally similar to benzodiazepine to reduce neuronal activity in the CNS.

Question 4

Zolpidem AE

Answer 4

Blurry vision, confusion, drowsiness, headache, impaired motor coordination, somnolence.

Question 5

Varenicline

Answer 5

Chantix

Question 6

Varenicline Class & Inidcation

Answer 6

Partial Nicotine Agent

Smoking Cessation

Question 7

Varenicline MOA

Answer 7

Selective agonist of the nicotine receptor in the CNS.

Question 8

Varenicline AE

Answer 8

Constipation, dream disorder, flatulence, suicidal thoughts, sleep walking

Question 9

Tolterodine

Answer 9

Detrol

Question 10

Tolterodine Class & Indication

Answer 10

Urinary Antispasmodic (Anticholinergic Agent)

-Overactive bladder or dyfunctional bladder

Question 11

Tolterodine MOA

Answer 11

Competitively binds to and antagonizes muscarinic receptors n the smooth muscle of the urinary bladder.

Question 12

Tolterodine AE

Answer 12

Constipation, dry mouth, blurry vision, urinary retention, dizziness, increase in pulse

Question 13

Tizanidine

Answer 13

Zanaflex

Question 14

Tizanidine Class & Indication

Answer 14

Centrally Acting Skeletal Muscle Relaxant

Muscle Spasms

Question 15

Tizanidine MOA

Answer 15

Functions as an agonist to the alpa-2 receptor in the CNS which increases the presynaptic inhibition that decreases spasticity but without significant reductions in blood pressure like with other alpha-2 agonists.

Question 16

Tizanidine AE

Answer 16

Dry mouth,dizziness, depression, mild reductions in blood pressure, musclce weakness, somnolence

Question 17

Ropinirole

Answer 17

Requip

Question 18

Ropinirole Class & indication

Answer 18

Dopamine Agonist

Parkinson’s disease, Restless leg syndrome

Question 19

Ropinirole MOA

Answer 19

Acts as an agonist to the D3 most but also D2 and D4 receptors in the CNS.

Question 20

Ropinirole AE

Answer 20

Dizziness, dyskinesia (uncontrollable and voluntary muscle movement), edema, hypotension, hallucination, GI, nausea, vomiting.

Question 21

Prochlorperazine

Answer 21

Compazine

Question 22

Prochlorperazine Class & indication

Answer 22

Antiemetic; 1st Gen. (Typical) Antipsychotic; Phenothiazine Derivative

Question 23

Propchlorperazine MOA

Answer 23

Antagonizes the D2 receptor in the CNS.

Question 24

Propchlorperazine AE

Answer 24

Drowsiness, fatigue, headache, neuroleptic malignant syndrome, QT prolongation, seizures.

Question 25

Phenytoin

Answer 25

Dilantin

Question 26

Phenytoin Class & Indications

Answer 26

Anticonvulsant Seizures

Question 27

Phenytoin MOA

Answer 27

Inhibits sodium channels and some calcium channels in nerves of the CNS therby inhibiting synaptic post-tetanic potentiation and propagation of electric discharge.

Question 28

Phenytoin AE

Answer 28

Gingival hyperplasia, ataxia, confusion, dizziness, hypertrichosis, tremor, rash.

Question 29

Oxybutinin

Answer 29

Ditropan Oxytrol for women OTC

Question 30

Oxybutinin Class & Indication

Answer 30

Urinary Antispasmodic Agent (Anticholinergic) Overactive Bladder

Question 31

Oxybutinin AE

Answer 31

Blurry vision, constipation, dizziness, dry mouth, urinary retention.

Question 32

Olanzapine

Answer 32

Zyprexa

Question 33

Olanzapine class & indication

Answer 33

2nd gen. Antagonist Antipsychotic Acute agitation from schizophrenia or bipolar mania; Bipolar disorder; Depression; Irritability from Autistic disorder; Schizophrenia; Tourette disorder.

Question 34

Olanzapine MOA

Answer 34

Antagonist to the D2 and 5-HT2 receptors in the CNS.

Question 35

Olanzapine AE

Answer 35

akathisia, dizziness, EPS, hyperlipidemia, hyperglycemia, nausea, vomiting, hyperprolactinemia, increased appetite, QT prolongation, somnolence, tremor, weight gain.

Question 36

Methocarbamol

Answer 36

Robaxin

Question 37

Methocarbamol class & indication

Answer 37

Centrally Acting Skeletal Muscle Relaxant Musculoskeletal pain or spasms.

Question 38

Methocarbamol AE

Answer 38

Confusion, dizziness, flushing, headache, nausea, vomiting, hemolytic anemia, jaundice, nystagmus (involuntary eye movement which causes vision blurred), rash, urticaria (hives), vertigo.

Question 39

Hydroxychloroquine

Answer 39

Plaquinel

Question 40

Hydroxychloroquine class & indication

Answer 40

Antimalarial Agent; Aminoquinoline Lupus erythematosus; Malaria (acute and chemoprphylaxis); Rheumatoid arthritis.

Question 41

Hydroxychloroquine AE

Answer 41

Abdominal pain, dizziness, headache, vision changes, retinopathy.

Question 42

Hydroxyzine

Answer 42

Atarax, Vistaril

Question 43

Hydroxyzine class & indication

Answer 43

1st Gen. Histamine-1 Receptor Antagonist; Antiemetic; Piperazine Derivative Uses: Anxiety, Antiemetic, Pruritis, Sedation Off Label: Seasonal Allergitis Rhinitis

Question 44

Hydroxychloroquine MOA

Answer 44

The exact mechanism of action is unclear but thought to interfere with digestive vacuole activity within parasites.

Question 45

Finasteride

Answer 45

Propecia, Proscar

Question 46

Finasteride class & indication

Answer 46

5-Alpha Reductase Inhibitor BPH, Alopecia (males)

Question 47

Finasteride AE

Answer 47

Dizziness, gynecomastia, impotence, reduced libido

Question 48

Hydralazine

Answer 48

Apresoline

Question 49

Hydralazine class & indication

Answer 49

Vasodilator- Antihypertensive Agent HTN

Question 50

Hydralazine AE

Answer 50

Dizziness, headache, hypotension, palpitations, reflex tachycardia, liver damage, drug-induced SLE(DILE)

Question 51

Levetiracetam

Answer 51

Keppra

Question 52

Levetiracetam class & indication

Answer 52

Anticonvulsant Myoclonic seizure; Partial seizure; Tonic-clonic seizure.

Question 53

Levetiracetam MOA

Answer 53

Unclear mechanism

Question 54

Levetiracetam AE

Answer 54

Agitation, depression, dizziness, fatigue, mood swings, somnolence.