Week 7 Drugs Flashcards

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0
Q

Adenosine Adenocard

Pharmacology and Actions

A

Slows conditions time through the AV node and interrupts the reentry pathway of the AV node and SA node. Half life of <10 seconds and does not cause a decrease in blood pressure.

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1
Q

Adenosine Adenocard

Class

A

Antiarrhythmic

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2
Q

Adenosine Adenocard

Indications

A

PSVT (refractory to vagal maneuvers)

Stable wide complex tachycardia thought to be reentry SVT

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3
Q

Adenosine Adenocard

Contraindications

A

Second or third degree AV block

Poisoning or drug induced tachycardia

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4
Q

Adenosine Adenocard

Precautions and Side Effects

A
Palpitations 
Hypotension 
Chest discomfort 
Headache/dizziness 
Respiratory distress
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5
Q

Adenosine Adenocard

Doses

A

Adult
6mg rapid IVO followed by a 10ml flush. Can be repeated once at 12mg. Adenosine should be given through the closest IV port using a large catheter

Pedi
0.1mg/kg IVP followed immediately by a 10ml flush. Can be repeated once at 0.2mg/kg. Adenosine should be given through the closest IV port using a large catheter

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6
Q

Calcium Chloride

Class

A

Electrolyte

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7
Q

Calcium Chloride

Pharmacology and Actions

A

Increases myocardial contractility and increases ventricular automaticity.

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8
Q

Calcium Chloride

Indications

A

Hyperkalemia
Hypocalcemia
Hypermagnesemia
Calcium channel blocker OD

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9
Q

Calcium Chloride

Contraindications

A

Ventricular fibrillation
Hypercalcemia
Digitalis toxicity

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10
Q

Calcium Chloride

Precautions and Side Effects

A

Hypotension
Bradycardia
Cardiac dysrhythmias
Cardiac arrest

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11
Q

Calcium Chloride

Doses

A

Adult
2-4mg/kg IV/IO every 10 min as needed
Pedi
20mg/kg IV/IO every 10 min as needed

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12
Q

Fentanyl Citrate, Sublimaze

Class

A

Narcotic analgesic

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13
Q

Fentanyl Citrate, Sublimaze

Pharmacology and Actions

A

A potent short acting narcotic agonist used for its analgesic properties. Fentanyl does not cause the vasodilation associated with morphine and so may be acceptable for use in hypovolemic patients.

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14
Q

Fentanyl Citrate, Sublimaze

Indications

A

Pain management

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15
Q

Fentanyl Citrate, Sublimaze

Contraindications

A

Myasthenia gravis

MAO inhibitors within 14 days

16
Q

Fentanyl Citrate, Sublimaze

Precautions and Side Effects

A

ALOC
Hypotension
Bradycardia
Cardiac arrests

17
Q

Fentanyl Citrate, Sublimaze

Doses

A

Adult
25-100mcg slow IV/IO over 2-3 min
1.0mcg/kg slow IV/IO over 2-3 min
Pedi
1.0mcg/kg slow IV/IO over 2-3min

18
Q

Isoproterenol, Isuprel

Class

A

Sympathomimetic

19
Q

Isoproterenol, Isuprel

Pharmacology and Actions

A

Isoproterenol increases cardiac output by increasing the strength of cardiac contraction and increasing rate (inotropy & dromotrophy). It also reduces peripheral vascular resistance and venous return.

20
Q

Isoproterenol, Isuprel

Indications

A

Symptomatic bradycardia refractory to atropine, pacing and dopamine
Severe status asthmaticus

21
Q

Isoproterenol, Isuprel

Contraindications

A

Cardiogenie shock

Acute myocardial infarction

22
Q

Isoproterenol, Isuprel

Precautions and Side Effects

A
Chest pain 
Palpitation 
Anxiety
Tachycardia 
Ventricular arrhythmias
23
Q

Isoproterenol, Isuprel

Dosage

A

Adult
2-10mcg/min
Status asthmaticus: 1-2 sprays MDI
Pedi
0.1mcg/kg/min titrated to cardiac rate and blood pressure
Status asthmaticus: same as adult

24
Q

Labetolol, Trandate

Class

A

Beta Blocker

25
Q

Labetolol, Trandate

Pharmacology and Actions

A

Labetolol decreases blood pressure by blocking stimulation of beta 1 (myocardial) and beta 2 (pulmonary, vascular and uterine) adrenergic receptor sites. It also has alpha 1 adrenergic blocking activity.

26
Q

Labetolol, Trandate

Indications

A

Management of an acute hypertensive crisis

27
Q

Labetolol, Trandate

Contraindications

A

Asthma
Heart blocks
Cardiogenie shock
Bradycardia

28
Q

Labetolol, Trandate

Precautions and Side Effects

A

Headache/dizziness
Bradycardia
Hypotension

29
Q

Labetolol, Trandate

Dosage

A

Adult
20mg slow IV/IO, repeat at 40-80mg every 10 min as needed up to a total of 300mg.
2mg/min up to a total dose of 300mg
Pedi
Not to be used for pediatrics

30
Q

Procainamide, Pronestyl

Class

A

Antiarrhythmic

31
Q

Procainamide, Pronestyl

Pharmacology and Actions

A

Procainamide is a antiarrhythmic regarded as a cardiac depressant. It suppresses phase 4 depolarization in the ventricles and Purkinje fibers, and decreases the automaticity of ectopic pacemakers. It also suppresses reentry arrhythmias by slowing conduction velocity.

32
Q

Procainamide, Pronestyl

Indications

A

PSVT uncontrolled by vagal maneuvers and adenosine
Recurrent VF/VT
Stable with complex tachycardia of unknown origin
Atrial fibrillation with rapid ventricular rate
WPW syndrome

33
Q

Procainamide, Pronestyl

Complications

A

Second or third degree AV block
Digitalis toxicity
Torsades de pointes
TCA overdose

34
Q

Procainamide, Pronestyl

Precautions and Side Effects

A

Use with caution in myocardial infraction, CHF hepatic or renal dysfunction
Hypotension in patients with impaired left ventricular function
It may cause arrhythmias in the presence of AMI, hypoklemia, or hypomagnesemia
Use with caution with other drugs that prolong the QT interval (Amiodarone)
Bradycardia, heart blocks
Widened QRS, prolonged PR or QP interval and ventricular ectopy

35
Q

Procainamide, Pronestyl

Dosage

A

Adult
Recurrent VF/VT: 20-50mg/min IV (total dose 17mg/kg)
Other indications: 20mg/min IV (total dose of 17mg/kg)
Pedi
Not intended for pediatrics