Week 7 Drugs

Question 0

Adenosine Adenocard

Pharmacology and Actions

Answer 0

Slows conditions time through the AV node and interrupts the reentry pathway of the AV node and SA node. Half life of <10 seconds and does not cause a decrease in blood pressure.

Question 1

Adenosine Adenocard

Class

Answer 1

Antiarrhythmic

Question 2

Adenosine Adenocard

Indications

Answer 2

PSVT (refractory to vagal maneuvers)

Stable wide complex tachycardia thought to be reentry SVT

Question 3

Adenosine Adenocard

Contraindications

Answer 3

Second or third degree AV block

Poisoning or drug induced tachycardia

Question 4

Adenosine Adenocard

Precautions and Side Effects

Answer 4

Palpitations 
Hypotension 
Chest discomfort 
Headache/dizziness 
Respiratory distress

Question 5

Adenosine Adenocard

Doses

Answer 5

Adult
6mg rapid IVO followed by a 10ml flush. Can be repeated once at 12mg. Adenosine should be given through the closest IV port using a large catheter

Pedi
0.1mg/kg IVP followed immediately by a 10ml flush. Can be repeated once at 0.2mg/kg. Adenosine should be given through the closest IV port using a large catheter

Question 6

Calcium Chloride

Class

Answer 6

Electrolyte

Question 7

Calcium Chloride

Pharmacology and Actions

Answer 7

Increases myocardial contractility and increases ventricular automaticity.

Question 8

Calcium Chloride

Indications

Answer 8

Hyperkalemia
Hypocalcemia
Hypermagnesemia
Calcium channel blocker OD

Question 9

Calcium Chloride

Contraindications

Answer 9

Ventricular fibrillation
Hypercalcemia
Digitalis toxicity

Question 10

Calcium Chloride

Precautions and Side Effects

Answer 10

Hypotension
Bradycardia
Cardiac dysrhythmias
Cardiac arrest

Question 11

Calcium Chloride

Doses

Answer 11

Adult
2-4mg/kg IV/IO every 10 min as needed
Pedi
20mg/kg IV/IO every 10 min as needed

Question 12

Fentanyl Citrate, Sublimaze

Class

Answer 12

Narcotic analgesic

Question 13

Fentanyl Citrate, Sublimaze

Pharmacology and Actions

Answer 13

A potent short acting narcotic agonist used for its analgesic properties. Fentanyl does not cause the vasodilation associated with morphine and so may be acceptable for use in hypovolemic patients.

Question 14

Fentanyl Citrate, Sublimaze

Indications

Answer 14

Pain management

Question 15

Fentanyl Citrate, Sublimaze

Contraindications

Answer 15

Myasthenia gravis

MAO inhibitors within 14 days

Question 16

Fentanyl Citrate, Sublimaze

Precautions and Side Effects

Answer 16

ALOC
Hypotension
Bradycardia
Cardiac arrests

Question 17

Fentanyl Citrate, Sublimaze

Doses

Answer 17

Adult
25-100mcg slow IV/IO over 2-3 min
1.0mcg/kg slow IV/IO over 2-3 min
Pedi
1.0mcg/kg slow IV/IO over 2-3min

Question 18

Isoproterenol, Isuprel

Class

Answer 18

Sympathomimetic

Question 19

Isoproterenol, Isuprel

Pharmacology and Actions

Answer 19

Isoproterenol increases cardiac output by increasing the strength of cardiac contraction and increasing rate (inotropy & dromotrophy). It also reduces peripheral vascular resistance and venous return.

Question 20

Isoproterenol, Isuprel

Indications

Answer 20

Symptomatic bradycardia refractory to atropine, pacing and dopamine
Severe status asthmaticus

Question 21

Isoproterenol, Isuprel

Contraindications

Answer 21

Cardiogenie shock

Acute myocardial infarction

Question 22

Isoproterenol, Isuprel

Precautions and Side Effects

Answer 22

Chest pain 
Palpitation 
Anxiety
Tachycardia 
Ventricular arrhythmias

Question 23

Isoproterenol, Isuprel

Dosage

Answer 23

Adult
2-10mcg/min
Status asthmaticus: 1-2 sprays MDI
Pedi
0.1mcg/kg/min titrated to cardiac rate and blood pressure
Status asthmaticus: same as adult

Question 24

Labetolol, Trandate Class

Answer 24

Beta Blocker

Question 25

Labetolol, Trandate Pharmacology and Actions

Answer 25

Labetolol decreases blood pressure by blocking stimulation of beta 1 (myocardial) and beta 2 (pulmonary, vascular and uterine) adrenergic receptor sites. It also has alpha 1 adrenergic blocking activity.

Question 26

Labetolol, Trandate Indications

Answer 26

Management of an acute hypertensive crisis

Question 27

Labetolol, Trandate Contraindications

Answer 27

Asthma Heart blocks Cardiogenie shock Bradycardia

Question 28

Labetolol, Trandate Precautions and Side Effects

Answer 28

Headache/dizziness Bradycardia Hypotension

Question 29

Labetolol, Trandate Dosage

Answer 29

Adult 20mg slow IV/IO, repeat at 40-80mg every 10 min as needed up to a total of 300mg. 2mg/min up to a total dose of 300mg Pedi Not to be used for pediatrics

Question 30

Procainamide, Pronestyl Class

Answer 30

Antiarrhythmic

Question 31

Procainamide, Pronestyl Pharmacology and Actions

Answer 31

Procainamide is a antiarrhythmic regarded as a cardiac depressant. It suppresses phase 4 depolarization in the ventricles and Purkinje fibers, and decreases the automaticity of ectopic pacemakers. It also suppresses reentry arrhythmias by slowing conduction velocity.

Question 32

Procainamide, Pronestyl Indications

Answer 32

PSVT uncontrolled by vagal maneuvers and adenosine Recurrent VF/VT Stable with complex tachycardia of unknown origin Atrial fibrillation with rapid ventricular rate WPW syndrome

Question 33

Procainamide, Pronestyl Complications

Answer 33

Second or third degree AV block Digitalis toxicity Torsades de pointes TCA overdose

Question 34

Procainamide, Pronestyl Precautions and Side Effects

Answer 34

Use with caution in myocardial infraction, CHF hepatic or renal dysfunction Hypotension in patients with impaired left ventricular function It may cause arrhythmias in the presence of AMI, hypoklemia, or hypomagnesemia Use with caution with other drugs that prolong the QT interval (Amiodarone) Bradycardia, heart blocks Widened QRS, prolonged PR or QP interval and ventricular ectopy

Question 35

Procainamide, Pronestyl Dosage

Answer 35

Adult Recurrent VF/VT: 20-50mg/min IV (total dose 17mg/kg) Other indications: 20mg/min IV (total dose of 17mg/kg) Pedi Not intended for pediatrics