Week 5 Drugs Flashcards
Amyl Nitrite
Pharmacology and Actions
VC
- Vasodilator and smooth muscle relaxant.
- converts hemoglobin to methemoglobin which combines with cyanide forming an non-toxic compound cyanmethemoglobin.
Amyl Nitrite
Class
Nitrate
Amyl Nitrite
Indications
Cyanide poisoning
Amyl Nitrite
Contraindications
None when used to manage an acute cyanide poisoning
Amyl Nitrite
Precautions and Side Effects
Headache/Dizziness Orthostatic vital signs Syncope Tachycardia N/V
Amyl Nitrite
Dosage
Adult
0.3ml ampule crushed every minute and inhaled for 15-30 seconds
Pedi
Same as adult
Etomidate
Class
General anesthetic
Etomidate
Pharmacology and Actions
UN
- ultra short non-barbiturate hypnotic anesthetic
- no analgesic effects and limited cardiovascular effects.
Etomidate
Indications
First line anesthetic for rapid sequence induction intubation
Etomidate
Contraindications
Hypersensitivity
Sepsis in pediatric patients
Etomidate
Precautions and Side Effects
Hypertension
Tachycardia/Bradycardia
Apnea
Etomidate
Dosage
Adult
0.1-0.3mg/kg IV over 15 to 30 seconds
Pediatric
Same as adult
Glucagon
Class
Hormone, anti-hypoglycemic
Glucagon
Pharmacology and Action
NRA
- Natural polypeptide hormone secreted by the pancreas.
- Released to breakdown stored glycogen to glucose and inhibit the synthesis of glycogen from glucose.
- Acts on receptor sites similar to those of epinephrine producing catecholamine like effects.
Glucagon
Indications
TBC
To increase blood sugar levels in hypoglycemia without vascular accesses
Beta-blocker overdose
Calcium channel blocker overdose