Week 6 Flashcards
Etomidate
etomidate Hypnotic-Anesthetic
Brand: Amidate
MOA: Works in CNS & suppresses mentation; GABA-like effects. Depresses brainstem.
IND: Anesthesia.
CON: Sensitivity, active labor, nursing mother (risk-benefit)
Adverse: Hypotension, respiratory depression, apnea, dysrhythmias, n/v, laryngospasm
Dose/Route: 0.2-0.6mg/kg over 30-60 seconds SLOW IV push/IO
Pedi: >10 as adult.
<10 not advised
SPCL: Pain at ejection site, used to prepare RSI, Preg. Class C
Succinylcholine
succinylcholine Depolarizing Neuromuscular Blocker
Brand: Anectine
MOA: skeletal muscle relaxant; paralytic. Competes with acetylcholine of the motor end plate of the
muscle cell.
IND: RSI
CON: Sensitivity, ICP, glaucoma, penetrating eye injury, crush injury, post acute burns
Adverse: Malignant hyperthermia, respiratory depression, apnea, dysrhythmia, HTN, Hyperkalemia, brady cardia
Dose/Route: 1-1.5mg/kg IV/IO
Pedi: 2-2.5mg/kg IV/IO
Special: IV 30-60 sec. onset; lasts 8 min. Prego class C. prolonged effect with nerve agents, causes muscle fasciculation(twitching), short term induction of coma
Propofol
propofol Sedative Hypnotic-Anesthetic
Brand: Diprivan
MOA: rapid & brief state of anesthesia.
IND: anesthesia, induction and maintenance of sedation
CON: sensitivity, hypovolemia, egg or soybean allergy.
Adverse: Hypotension, apnea, bradycardia, dysrhythmia, pain @ injection site, seizures, priapism, coma, death
Dose/Route: 1-3mg/kg induction IV/IO
Pedi: 2.5-3.5 mg/kg IV, IO
Maintenance Infusion: 25-75 mcg/kg/min
Pedi: 125-300mcg/kg/min
Special: Prego Class c, short recovery time, geriatrics 80% of dose
Midazolam
midazolam Benzodiazepine
Brand: Versed
MOA: short acting CNS depressant. Enhances GABA brain neurotransmitters. Sedative hypnotic, used as a tranquilizer
IND: Sedation, anxiety, pre-med for cardioversion, seizures, chemical restraint
CON: Sensitivity, pregnancy, glaucoma, shock, alcohol coma
Adverse: respiratory depression/arrest, drowsiness, hypotension, n/v, headache, “transient retrograde amnesia.” PVC, Hypotension
Dose/Route: 1-2 mg IV/IO/IN
0.07-0.8 mg/kg IM
Pedi: 0.05-0.07mg/kg up to 0.4mg
Special: Prego Class D, caution with other CNS depressants, Flumazenil is antidote
