week 3

Question 1

Ondansetrone

Answer 1

Ondansetrone Antiemetic

Brand: Zofran

MOA: Selectively antagonizes Serotonin receptors. Causes CNS depression.

IND: N/V (More specifically to cardiac patients; prevents extra workload and anxiety) motion sickness

CON: Hypersensitivity, Liver disease, GI obstruction

Adverse: headache, light headed/dizzy, tired, constipated, prolonged QT

Dose/Route: 4-8 mg SLOW IV push, IO, PO
Pedi—0.1mg/kg up to 4mg SLOW IV push

Special: Pregnancy Class B, lowers mentation of patients on SSRI (Serotonin, selective reuptake inhibitors).

Question 2

Ketorolac

Answer 2

ketorolac NSAID

Brand: Toradol

MOA: Decrease responsiveness of pain receptors; inhibits inflammation & pain. Antipyretic, analgesia, anti-inflammatory

IND: Acute moderate-severe pain.

CON: Hypersensitivity, Peptic ulcers, GI Bleed, renal insufficiency and hypovolemia,

Adverse: headache, drowsiness, N/V/D, dyspepsia, edema

Dose/Route: 30mg IV not to exceed 120mg daily
60mg IM not to exceed 120mg daily (IV, IO, IM, PO)
*65 y/o use ½ dose as adult
Pedi not indicated

Special: Pregnancy Class C, solution yellow tint, be mindful of bleeding or surgical procedures.

Question 3

Hydromorphone

Answer 3

hydromorphone Narcotic Opioid analgesic

Brand: Dilaudid

MOA: Pure opioid agonist. Bind to opiate receptors.

IND: Severe Pain.

CON: Hypersensitivity Shock, hypoperfusion, hemorrhage, head injury

Adverse: Respiratory depression, decreased level of consciousness, hypotension, bradycardia, nausea, dizziness, constipation.

Dose/Route: 1-2mg IM
0.2-1mg IV q2-3 hrs
2-4 mg tablet q4-6 hrs
Pedi—0.015mg/kg SIVP

Special: Avoid other CNS substances (drugs, alcohol). Class II Narcotic

Question 4

Sublimaze

Answer 4

sublimaze Narcotic Opioid Analgesic

Brand: Fentanyl

MOA: Pain reduction. Binds to opiate receptors & produces euphoria and analgesia.

IND: moderate to severe Pain, pretreatment for RSI

CON: Hypersensitivity, TBI, Respiratory Depression, M.A.O.I, Head injury

Adverse: Respiratory Depression, Hypotension, bradycardia, syncope, N/V, dizziness

Dose/Route: pedi/adult 1-2 mcg/kg IM, IV, IO, IN
RSI induction 3mcg/kg IV push 3 min before intubation

Special: Pregnancy Class C. Dose should be individualized, Class II narcotic