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Bacteriology > Week 6 > Flashcards

Week 6 Flashcards

1
Q

97% of Staphylococcus aureus isolated in human produce the enzyme

A

Coagulase

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2
Q

enzyme that reacts with the blood factor in the plasma to initiate clot formation

A

Coagulase

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3
Q

enhance the deposition of the fibrin around the organism to protect them from phagocytosis

A
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4
Q

counteracts the action of fatty substances secreted by the body

A

Lipase

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5
Q

help in the colonization of organism – oily skin surfaces

A

Lipase

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6
Q

found in the intracellular ground substance of connective tissue

A

Hyaluronidase

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7
Q

promote invasion of organism by digesting the intracellular ground substance “glue” (hyaluronic acid) that binds connective tissue in host tissue

A

Hyaluronidase

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8
Q

proteolytic enzyme with fibrinolytic activity

A

Staphylokinase

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9
Q

causes dissolution of clot – spread infection further

A

Staphylokinase

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10
Q

enzymatically and antigenically distinct from Streptokinase of Streptococci

A

Staphylokinase

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11
Q

Production by most strain of Staphylococcus

A

Staphylokinase

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12
Q

degrade nucleic acid DNA

A

Nuclease (DNAse)

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13
Q

most specific test for Staphylococcus aureus

A

Nuclease (DNAse)

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14
Q

found in cell surfaces of 90% - 96% of Staphylococcus aureus

A

Nuclease (DNAse)

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15
Q

lyse RBC by destroying their membrane

A

Hemolysins/Cytolytic Toxins

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16
Q

producing tissue damage;

A

Hemolysins/Cytolytic Toxins

17
Q

abscess formation

A

Hemolysins/Cytolytic Toxins

18
Q

Chromosomal mediated

A

Hemolysins/Cytolytic Toxins

19
Q

A heterogenous protein that acts on a broad spectrum of eukaryotic cell membranes.

A

A Hemolysin

20
Q

Degrades sphingomyelin, and is therefore toxic for many kinds of cells including human red blood cells

A

B toxin

21
Q

most powerful toxin that lyses RBC of various animals (platelets and macrophages= tissue damage)

A

A-hemolysis

22
Q

produce hemolysis in blood agar medium

A

A hemolysis

23
Q

Predominant hemolysin produced by S. aureus

A

A-hemolysin

24
Q

Heat labile

A

B toxin

25
Q

heterogenous and dissociates into subunits in non – ionic detergents.

A

8 Toxin

26
Q

Disrupts biologic membranes and may have a role in Staphylococcus aureus diarrheal diseases.

A

8 toxin

27
Q

Active against macrophages, lymphocytes, and neutrophil.

A

8 toxin

28
Q

A leukocidin that lyses white blood cells.

A

Y toxin

29
Q

Composed of two proteins designated S and F which may interact with the two proteins of Panton – Valentine Leukocidin.

A

Y Toxin

30
Q

composed of two (2) protein components that can kills white blood cells of humans and incapacitate the phagocytic line of the defense of the host. (cause pore formation in the cellular membrane necrosis and severe inflammation)

A

Panton – Valentine Leukocidin

31
Q

An important virulence factor in CA – MRSA infections.

A

Panton – Valentine Leukocidin

32
Q

Encoded on a mobile phage

A

Panton – Valentine Leukocidin

33
Q

stable and resistant to the action of gut enzymes

A

Heat

34
Q

Produce when Staphylococcus aureus grows in carbohydrate and protein foods.

A

Enterotoxins

35
Q

Most often EXCRETED from the cell; but some accumulate inside the cell are either injected directly or are released by cell lysis.

A

Enterotoxins

36
Q

Types of enterotoxins:

most frequently associated with Staphylococcus food poisoning

A

A & D

37
Q

Types of enterotoxins:

associated with hospital acquired infection
(nosocomial); ingestion of 25μg results in
vomiting and diarrhea (pseudomembranous enterocolitis- milk product)

A

B

38
Q

Types of enterotoxins:

Recently recognize toxin, associated with toxic shock syndrome

A

F

39
Q

2 types of Exfoliative Toxins

A

Exfoliative Toxin A & Exfoliative Toxin B

Bacteriology (13 decks)

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