Week 5 - Rheumatoid Arthritis Flashcards
People with RA are at risk for what 4 things?
- decreased flexibility
- muscle atrophy
- decreased muscle strength
- reduced cardiovascular endurance
one type of INFLAMMATORY polyarthritis characterized by a prolonged course of exacerbation and remission of joint pain and swelling which frequently leads to deformity and permanent disability.
RA
one type of INFLAMMATORY polyarthritis characterized by a prolonged course of exacerbation and remission of joint pain and swelling which frequently leads to deformity and permanent disability.
RA
what is RA?
a chronic inflammatory disease with symmetrical poly-articular inflammation, morning stiffness, malaise, and fatigue.
RA is a ___ disease affecting not only the ___ joints but also blood vessels, heart, lungs, eyes and other non-articular systems.
systemic, synovial
name 4 associated problems with RA.
- skeletal
- respiratory
- drugs
- other
name the 5 stages of joint changes in RA.
- healthy joint
- synovitis
- pannus
- fibrous ankylosis
- bony ankylosis
- synovial membrane inflamed and thickened
- bones and cartilage gradually eroded
synovitis
extensive cartilage loss; exposed and pitted bones
pannus
joint invaded by fibrous connective tissue
fibrous ankylosis
bones fused
bony ankylosis
inner membrane of synovial joints which secretes synovial fluid into the joint cavity.
synovial membrane
RA MUST have ___ involvement.
hand
name the criteria for an RA diagnosis.
- symmetrical polyarthritis - usually hands
- persisted more than 60 days
- systemic fatigue and malaise
self limited polyarthritis, resolves
type 1 - RA
persistent disease but does NOT lead to long term consequences
type 2 - RA
progressive disease, x-ray changes, decreased function, work disability
type III - RA
independent in ADLs, IADLs, vocation, avocation
type I - RA functional classification
able to do ADLs, IADLs, work, NO avocation
type II - RA functional classification
able to do self-care and limited work
type III - RA functional classification
all activities limited
type IV - RA functional classification
a medical strategy that sets remission or low disease activity as a goal; specific disease management targets are set.
Drug Therapy: Treat to Target (T2T)
Name 4 categories of drugs involved in RA treatment.
- non-steroidal anti-inflammatory (NSAIDs)
- disease modifying anti-rheumatic (DMARDs)
- corticosteroids
- analgesic drugs
what is the goal of drug therapy for RA?
clinical remission