Week 3: Differentiation And Development Flashcards

1
Q

What is the fate of cells during development?

A

The fate of cells is determined by their position and molecular signals during development.

This includes processes such as differentiation and the influence of neighboring cells.

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2
Q

What are somatic cells?

A

Somatic cells are all cells in the body except sperm and egg cells.

They contain the same DNA but are differentiated into various cell types.

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3
Q

What is a zygote?

A

A zygote is a diploid cell formed by the fusion of sperm and egg during fertilization.

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4
Q

What is the difference in chromosome number between somatic cells and gametes?

A

Somatic cells are diploid (2n) while gametes (sperm and egg) are haploid (n).

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5
Q

How many different cell types are found in the human body?

A

More than 210 different cell types.

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6
Q

What are model organisms used for in developmental biology?

A

Model organisms are used to study embryo development due to ethical and practical constraints of using human embryos.

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7
Q

Name a few characteristics that make a good model organism.

A

A good model organism should be:
* Easy to work with
* Produce a lot of eggs and embryos
* Transparent
* Large
* Develop outside the body.

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8
Q

What is C. elegans?

A

C. elegans is a transparent nematode used as a model organism in developmental biology.

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9
Q

What is the significance of the grey crescent in frog development?

A

The grey crescent is the region around which the dorsal surface of the frog embryo will develop.

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10
Q

What is gastrulation?

A

Gastrulation is the process where cells rearrange and differentiate to form tissue layers.

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11
Q

What are the three primary germ layers formed during gastrulation?

A

The three primary germ layers are:
* Ectoderm
* Mesoderm
* Endoderm.

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12
Q

What role does VegT protein play in embryonic development?

A

VegT protein is a transcription regulator that activates genes coding for mesoderm and endoderm.

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13
Q

What is the difference between totipotent, pluripotent, and multipotent cells?

A

Totipotent cells can become all cell types, pluripotent cells can become most cell types, and multipotent cells can become several cell types.

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14
Q

What is the Weismann Barrier?

A

The Weismann Barrier states that information is inherited via the germ line, while somatic cells can influence the germ line through epigenetic changes.

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15
Q

True or False: The development of cells is completely predetermined and cannot change.

A

False. Cell fate can be influenced by position and neighboring cells.

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16
Q

Fill in the blank: The process of differentiation can be reversed through induced _______ cells.

A

[pluripotent]

17
Q

What happens to the fate of a blastomere if it is moved during early development?

A

The fate of the blastomere can change based on its new position and the influence of neighboring cells.

18
Q

What is the major conclusion about cell fate in the blastula?

A

The final fate of blastomeres is determined by their position within the blastula.

19
Q

How does human embryonic development differ from that of Xenopus?

A

Human development is more complicated, with more steps and earlier differentiation into inner cells and trophoblasts.