Week 3 Flashcards
In general terms, what is the First stage of Aerobic ATP production ?
Generation of Acetyl- CoA
In general terms, what is the Second stage of Aerobic ATP production ?
Oxidation of Acetyl CoA (Krebs Cycle)
In general terms, what is the Third stage of Aerobic ATP production ?
Oxidation Phosphorylation (ATP production in ETC)
Where is Acetyl CoA generated?
Mitochondria
What is the primary function of the Krebs cycle
Produce electron carriers;
NADH, FADH, H+
How many turns of the Krebs Cycle result from 1 Glucose Molecule ?
2
What is the first step of the Krebs cycle?
Removal of carbon from Pyruvate to form Acetyl-CoA
What enzyme is responsible for the transformation of Pyruvate into Acetyl-CoA ?
Pyruvate Dehydrogenase
What is the first oxidation reduction reaction of the Krebs cycle and what results from this?
Isocitrate > alpha-Ketoglutarate (enzyme = isocitrate dehydrogenase)
Results in : NADH and CO2
What is the rate limiting enzyme of the Krebs cycle
Isocitrate Dehydrogenase
What is the second oxidation reduction reaction of the Krebs cycle and what results from this?
Alpha-ketoglutarate > Succinyl-CoA (enzyme = alpha-ketoglutarate Dehydrogenase)
Results in; NADH &CO2
In the Krebs cycle, What does the reaction of Succinyl-CoA > Succinate produce ?
GDP > GTP > ADP > ATP
What reaction produces FADH in the Krebs cycle ?
Succinate > Fumarate
What is the last step in the Krebs Cycle and what does it result in?
Malate > Oxaloacetate
Results in; NADH
What stimulates the Krebs cycle
ADP & Calcium
