WEek 3

Question 1

What are the steps of depolarization?

Answer 1

• depolarization of presynaptic terminal
• Ca entry
• exocytosis of transmitter
• postsynaptic receptor action potential
• Ion channels open in post synaptic membrane

Question 2

____________ is caused by G(k)> G(Na)

Answer 2

hyper polarization

Question 3

If potassium current> sodium current, the membrane potential will tend to move toward E(k)

Answer 3

equilibrium of potassium

Question 4

___________ no net flux of ions occur

Answer 4

resting potential

Question 5

_________ active change in membrane potential via via changing ionic conductances.

Answer 5

action potential

Question 6

Ohms law in terms of conductance

Answer 6

I= G(Vm-Ek)

Question 7

simulus -> membrane depolarization -> Na+ channels open (ΔGna) change in sodium conductance

Answer 7

stimulus -> membrane depolarization -> Na+. channels open (ΔGna) -> Na floods into cell -> action potential

Question 8

change ion __________ and current drive action potentials

Answer 8

conductance

Question 9

___________ TTX blocks voltage gated sodium channels. No outward current

Answer 9

TTX tetrodotoxin

Question 10

_____________ blocks potassium channels. No outward current

Answer 10

TEA tetra ethyl amine.

Question 11

high _____________ inside the cell

Answer 11

potassium

Question 12

hugh _________________ outside the cell

Answer 12

sodium

Question 13

__________________ allowed resting conditions to be maintained

Answer 13

sodium potassium pump

Question 14

________________ sodium channels are inactivated

Answer 14

absolute refractory period

Question 15

______________ much harder to reach action potentials. Larger current needed. If generated, the action potential will be small due to the conductance of Gnarling not resetting and not as many sodium channels

Answer 15

relatively refractory period

Question 16

________________:

• quick rapid adapting response
• allows us to determine small changes

Answer 16

phasic response

Question 17

______________:

• slow adapting
• help us determine the length of adaptation

Answer 17

tonic response

Question 18

___________ electrical coupling, the allows for instaneous neural signaling. Caused by two neurons being tightly opposed. Allows the cytoplasm to be tightly opposed

Answer 18

Gap junctions

Question 19

How were gap junctions found

Answer 19

• dye coupling

- Vm change

Question 20

steps of synaptic physiology

Answer 20

Depolarizing of presynaptic terminal -> Ca entry -> exocytosis of transmitter -> postsynaptic receptor act. -> ion channels open in postsynaptic membrane