Week 2 Flashcards
___________ signaling carried throughout the blood stream. Requires receptors
endocrine
________________ can be between cells or within one cell (autecrine)
paracrine
______________ can diffuse freely
free radicals
_______________ signaling occurs across a cleft. A receptor is located on one side of a cell
synaptic
cell signaling molecules:
__________ no syntheses and can not be stored
gaseous molecules
cell signaling molecules:
____________ synthesized and not stored
steroids
cell signaling molecules:
________________ can be synthesized and not stored
steroids
cell signaling molecules:
__________ synthesized and not stored
peptides
what are the steps of peptide amine signaling (ion channel linked receptor)
- ligand binds to receptor
- ligand causes conformational change
- ion can now flow
what are the steps of peptide amine signaling (G protein linked receptor)
- ligand binds receptor
- G protein is activated
- G protein activates other enzyme
What are the steps of peptide amine signaling-> enzyme linked receptor
inactive enzyme, protein binds activating receptor
Enzyme linked receptor and direst phosphorylation or dephosphorlyation:
- when enzymes are active, they encage a phosphatase reaction or dephosphorylation
- When the enzyme is inactive, they encourage a kinase reaction or phosphorylation
__________ activation of phosphorylation or kinases by exchanging GTP for GDP
GTP and GDP exchange
___________________ stress response
fight or flight
What is released during a flight or flight response and how does this affect glucose release
- epinephrine induces rapid glycogen breakdown in skeletal muscle. (adrenergic cascade)
- 1 molecule of epinephrine releases 10^8 glucose molecules