week 10 - skeletal dysplasia

Question 1

generalised sclerosis

Answer 1

abnormal metaphyseal and periosteal ossification caused by either excessive osteoid production or deficient osteolysis
radiographic feature = increase bone density

Question 2

osteopetrosis

Answer 2

widespread osteopetrosis and increase in overall skeletal mass
- consequence of defective osteoclast function coupled with a defect in bone resorption, increased bone density and reduction in bone marrow spaces