Week 10 Neurocognition II Flashcards
Acute Stoke
Disruption of perfusion of O2 & nutrients to cerebral tissues
Ischemic Stroke
Blocked vessel
Most common
Hemorrhagic Stroke
Bleeding
Less common
Transient Ischemic Attack
- Neurological dysfunction that resolves
- Without imaging evidence of infarction
Ischemic Stroke - Large Artery
- BAD
- Atherosclerotic plaque formation
- Occlusion = brain perfusion interrupted
Ischemic Stroke - Small Artery
- Emboli
- High BP
- Vasospasm
Ischemic Stroke - Cardiogenic Embolic
- Clot from heart goes to brain
- A fib
Ischemic Stroke - Cryptogenic
Idiopathic
Left Sided Stroke Impact
- Right side paralysis
- Speech issues
- Language issues
- Memory loss
- Slow & cautious
- Right sided neglect
Right Sided Stroke Impact
- Left sided paralysis
- Vision issues
- Memory loss
- Fast & risky - impulse control
- Left sided neglect
Treatment Timeline - Ischemic
- <4.5h eligible for thrombolysis
- <6h eligible for endovascular thrombectomy
Imaging
- Non-contrast CT/MRI
- Diagnosis ischemic vs hemorrhagic
Thrombolysis
- Fibrinolytic therapy: tissue plasminogen activator
- Given within 4.5 hours can dissolve clot
- Anticoagulants given to prevent further clots
Endovascular Thrombectomy
Removal of thrombus under image guidance
Intercranial Hemorrhage
- Bleeding into brain tissue
- Due to ruptured vessel
Subarachnoid Hemorrhage
Bleeding into subarachnoid space or AVM
Hemorrhage Results in
- Blood compressing brain tissue
- ICP increases
- Cerebral edema
Hemorrhagic Stroke S/S
- Rapid onset (compared to ischemic)
- Severe headache
- N/V
- Confusion, altered LOC
- 1 sided weakness
- Impaired speech
- Fixed pupils
Hemorrhage Medical Interventions
- Endovascular procedure
- Surgical procedure
ABC Management
- Swallowing
- Head of bed 30 degrees - reduce aspiration
- Oxygenation
- BP
- Fluids for perfusion
Increased ICP Management
- Cerebral edema/blood in cranial cavity
- Osmolar diuretics - mannitol
- Increase osmolality of blood
- Increase value in intravascular space
- Diuretics to excrete
- Electrolyte imbalance & seizure caution***
- Elevate head of bed - 30 degrees
- Low stim environment
Seizure
- Excessive & acute onset
- Electrical activity of cerebral neurons
- Causes abnormal motor, sensory, autonomic, psychiatric activity
Seizure Pathology
- Excitatory neurons releasing glutamate
- Not enough inhibitory neurons releasing GABA
Epilepsy
2 unprovoked seizures occurring 24 hrs apart