Wed - huntingtons drugs Flashcards
1
Q
Haloperidol
mech
side effects
A
DA (D2) antagonist, typical antiphyschotic
risk: tardive dyskinesia
2
Q
atypical antipsychotics
3 of them
some pearls w/ them
A
olanzapine - weight gain, sedation
risperidone
clozaril - DA antagonist, risk of agranulocytosis
3
Q
tetrabenazine
A
monoamine depleting agent
high binding affinity in caudate, putamen
SE: anxiety, depression
extrapyramidal Sx: opposite of huntington’s disease
4
Q
valproic acid
mech
SE
A
Anticonvulsant and mood stabilizer
increases GABA levels
SE: weight gain
5
Q
lithium
mech
A
stops reuptake of 5-HT, NE
6
Q
First line of Tx for chorea?
A
benzodiazepines
