Water,electrolytes and Hypertension Flashcards
Functions of water ( 8 points)
- Nutrient absorption and transport
- Biochemical reactions
- Solvent
- Lubricant( in joints,eyes)
- Shock absorber ( pregnancy, baby in the fluid)
- Temperature regulation ( sweating)
- Blood volume( not enough influences blood pressure)
- Excretion of waste
Electrolytes: examples and 3 functions, definition
Anions and cations that allow the electrical impulse to pass. Na, K,Mg,Ca
- Fluid compartments and balance
- Acid/base balance
- Muscle contraction
- Conduction of nerve impulse
Requirements for water
1 to 1.5 mL/kcal/energy expenditure
2.2 L for women and 3 L for men
Increased intake of water for
- Pregnant, lactating women
- Diarrhea,vomiting
- Fever( because you are sweating)
- Heavy exercise
- Elderly
- Air travel
- Hot environment
When we are thirsty , does it mean that we are starting to be dehydrated?
No, we are already
Do we need to drink 8 cups of water?
No, it is a myth. We get water from food as well
What is the volume of obligatory urine excretion
500 ml
Water sources
Beverages, food, metabolism ( TCA cycle)
Water losses
Urine,sweat,breath,feces
What is the correlation between water sources and water losses
They are equal
Types of fluids around the cell
Intracellular
Intercellular/interstitial
Extracellular
What is the overall charge between intracellular and extracellular fluid
0
What anions and cations in the cell and outside of the cell
Outside - Na,Cl
Inside-K,Phosphate ,Mg,S
What does sodium do ?
- Blood volume regulation
- Na K ATPase
What happens with high and low concentrations of K?
- High blood concentrations ( heart attack)
- Deficiency( losses-vomiting and diarrhea, diuretics-for hypertension) - bot absorbing water in the colon or in the kidney
How much fluid is secreted and reabsorbed in GI tract
8-10 L/day
Losses of water
- Sweating,bleeding,GI loss( vomiting, diarrhea)]
- Diabetes- lose glucose and water
What is the replacement for water and the target population
When vomiting, diarrhea, prolonged flu
Also called oral rehydration therapy
Sugar , salt and water
How the kidney works
Glomerrus, tubuls, etc.
What happens as the response to low blood pressure and low blood volume?
Receptors in kidneys detect that———>Renin in kidneys—-> Renin converts Angiotensinogen to Angiotensin I——> Angiotensin I to Angiotensin II————>Retains Na and water , constricts blood vessels—-> increase blood pressure
Angiotensin II——>antidiuretic hormone(ADH )—-> retains water( and thereby reabsorption of Na and excretion of K)—–> higher blood pressure
Angiotensin II——>Aldosterone—-> Retains sodium, excretes potassium( retains water)—–> higher blood pressure
Thirst and satiety are sensed by
Mouth,hypothalamus and nerves. You can be thirsty, but you will think you are hungry
Water intoxication
When you drink 10 L in 2 or 3 hours. Na level drops—>causes the water to go into cell balance the difference in concentrations ( can explode)