Wallis HPV

Question 1

HPV is a ____ stranded ____ virus

Answer 1

ds; DNA

Question 2

How can HPV be transmitted?

Answer 2

Sexually, but does not need penetrative sex, just any skin to skin contact (transmitted orally, vaginally, anally)

Question 3

What can help reduce risk of genital HPV transmission?

Answer 3

Condoms to reduce risk!!!

Question 4

Risk factors for HPV?

Answer 4

Young age, early age at first intercourse, having multiple partners, smoking, immunocompromised

Question 5

Risk factors for HPV persistence?

Answer 5

Cig smoking, immunocompromised, HIV

Question 6

Even after treatment of genital warts, what can still happen? What do currently available therapies accomplish? If there is persistence after 3 months even with treatment, what should be considered?

Answer 6

Recurrence due to HPV still lingering; reduce but probably don’t eliminate infectivity;
consider a biopsy to exclude a premalignant or neoplastic condition, especially if patient is immunocompromised

Question 7

For patient applied therapy, what are three different treatments? What’s administered by the provider?

Answer 7

Podofilox, imiquimod, sinecatechins;

cryotherapy, podophyllin in tincture of benzoin, trichloroacetic or bichloroacetic acid, surgical removal

Question 8

What are HPV DNA tests approved for?

Answer 8

Triage women with atypical squamous cell pap test results and as an adjunct to pap screening for cervical cancer in women over 30

Question 9

What are some treatment options for cervical dysplasia? CIN?

Answer 9

Repeat testing, colposcopy with biopsies, LEEP; ablative therapy, excisional therapy like LEEP

Question 10

What are the HPV vaccines and who are they good for?

Answer 10

Gardasil (age 9) and gardasil quadravalent (6, 11, 16, 18, for ages 12 up through age 26 in women and 21 in men if they missed the age deadlines); cervarix (16, 18), good for ages 9-25 and should ideally be given before sexual activity