W7 - Allergic Disease Flashcards
what is an allergy classified as
IgE and non-IgE-mediated immune reaction
what is a food allergy
“An adverse health effect arising from a specific immune response that occurs reproducibly on exposure to a given food”
what is the classic symptoms of an IgE mediated reaction
Quick onset
Anaphylaxis
Well defined mechanism
Easy to diagnose
Validated tests
what are the classic symptoms of non-IgE medicated reaction
Delayed onset
Eczema, GORD
Mechanism unclear
Harder to diagnose
No validated tests
what are key questions to ask in an allergy history
onset of symptoms
quantity of food
history of atopy
what are some associated disorders with food allergy’s
eczema
asthma
hay fever
animal allergy
what is the gold standard test for food allergy
oral food challenge
does a positive allergy test mean that you have an allergy
no - just means its more likely
does a stronger reaction to an allergy test mean a bigger allergy
no
what does specific IgE testing test for
sensitisation only
false positives are very common
what is the first line antihistamines
cetirizine
who can have an adrenaline autoinjector
cardiovascular or respiratory reaction
exercise induced anaphylaxis
who cannot have an epipen
any reaction to small amount of food
mild reaction
what is the test for non-IgE mediated testing
no test
take out and then reintroduce in a few weeks
which allergy’s are generally outgrown and disappear over time
milk egg and wheat
