W33/L3 Flashcards
1
Q
What’s the most common mode of HIV transmission worldwide?
A
Heterosexual contact
2
Q
What’s the most common mode of HIV transmission in Aus?
A
Homosexual contact
3
Q
What sort of capsid symmetry does HIV have?
A
Icosahedral
4
Q
Is HIV enveloped? What’s the result?
A
Yes - it’s very susceptible in the environment
5
Q
What sort of genome does HIV have?
A
+sense ssRNA
6
Q
Which receptor does HIV use?
A
CD4
7
Q
Which cells have the CD4 receptors?
A
T-lymphocytes
Macrophages
8
Q
What’s the fist thing the virus does while intracellular?
A
Reverse transcription of its RNA to make a cDNA (copy DNA)
9
Q
What are the two co-receptors for HIV?
A
CCR5
CXCR4
10
Q
Which is the predominant co-receptor in early infection?
A
CCR5
