W34/L1: Leukaemia Flashcards
1
Q
What environmental factors can predispose to leukaemia?
A
Radiation
Benzene
Alkylating agents
Tobacco
2
Q
What sort of DNA alteration is the main cause of leukaemia?
A
Chromosomal translocations
3
Q
What’s the most common type of chronic leukaemia in the west?
A
Chronic lymphocytic leukaemia (CLL)
4
Q
What do you see on a blood smear of acute leukaemia?
A
Lots of large blasts
5
Q
What do you see on a blood smear of CLL?
A
Large number of what appear to be normal lymphocytes
Smear cells
6
Q
What it the name of the drug that is an inhibitor of the tyrosine kinase BCR-ABL?
A
Imatinib
